[1]王培鑫,赵军,王兴盛,等.雌激素与特发性脊柱侧弯相关性的研究进展[J].临床小儿外科杂志,2024,(05):493-495.[doi:10.3760/cma.j.cn101785-202208053-019]
　Wang Peixin,Zhao Jun,Wang Xingsheng,et al.Research advances of correlation between estrogen and idiopathic scoliosis[J].Journal of Clinical Pediatric Surgery,2024,(05):493-495.[doi:10.3760/cma.j.cn101785-202208053-019]
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雌激素与特发性脊柱侧弯相关性的研究进展

《临床小儿外科杂志》[ISSN:1671-6353/CN:43-1380/R] 卷: 期数: 2024年05 页码: 493-495 栏目: 综述 出版日期: 2024-05-01
Title:
Research advances of correlation between estrogen and idiopathic scoliosis
作者:
王培鑫1;  赵军2;  王兴盛2;  徐世红2;  姜朝阳2;  王小强2;  杨红娟1
1 甘肃中医药大学中医临床学院, 兰州 730000;
2 甘肃省中医院创伤中心, 兰州 730050
Author(s):
Wang Peixin1;  Zhao Jun2;  Wang Xingsheng2;  Xu Shihong2;  Jiang Zhaoyang2;  Wang Xiaoqiang2;  Yang Hongjuan1
1 Clinical College of Traditional Chinese Medicine, Gansu University of Traditional Chinese Medicine, Lanzhou 730000, China;
2 Trauma Centre, Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, China
关键词:
雌激素; 脊柱疾病; 外科手术; 儿童
Keywords:
Estrogens; Spinal Diseases; Surgical Procedures;  Operative; Child
DOI:
10.3760/cma.j.cn101785-202208053-019
摘要:
特发性脊柱侧弯(idiopathic scoliosis,IS)作为儿童青少年常见的脊柱疾病之一,影响因素复杂,给儿童青少年的生活质量和身心健康带来严重影响。雌激素作为影响特发性脊柱侧弯发生、发展的一个重要因素,可通过异常调节骨代谢、经受体作用于椎旁肌肉等直接或间接影响脊柱侧弯的发生、发展。研究雌激素对脊柱侧弯进展的影响,可为脊柱侧弯病因研究和治疗提供新的策略。本文就雌激素与特发性脊柱侧弯相关性的研究进展进行综述。
Abstract:
As one of common spinal diseases in children and adolescents,idiopathic scoliosis (IS) has so many complex influencing factors as to seriously affect the quality of life and physical and mental health.Estrogen may directly or indirectly modulate the occurrence and development of IS through abnormal regulations of bone metabolism and its effect on paravertebral muscles via receptors.Elucidating the underlying mechanism offers a novel therapeutic strategy.This review summarized the latest researches on correlation between estrogen and IS.

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相似文献/References:

[1]刘德鸿,肖现民,郑珊,等.雌激素对肠缺血再灌注损伤时MDA、MPO影响的研究[J].临床小儿外科杂志,2007,6(01):9.
[2]赵军,王培鑫,王兴盛,等.青少年特发性脊柱侧凸脊柱融合术的研究进展[J].临床小儿外科杂志,2023,22(07):698.[doi:10.3760/cma.j.cn101785-202209052-018]
　Zhao Jun,Wang Peixin,Wang Xingsheng,et al.Research advances in spinal fusion for adolescent idiopathic scoliosis[J].Journal of Clinical Pediatric Surgery,2023,22(05):698.[doi:10.3760/cma.j.cn101785-202209052-018]

备注/Memo

收稿日期:2022-08-28。
基金项目:省级重点人才项目(甘组通字【2022】77号); 联合科研基金重大项目(23JRRA1529); 临床医学研究中心建设项目(21JR7RA681)
通讯作者:赵军,Email:673078008@qq.com

更新日期/Last Update: 1900-01-01