Wen Xu,Li Ning,Song Hongcheng,et al.Clinical features and treatment analysis of metanephric adenoma in children: a series[J].Journal of Clinical Pediatric Surgery,2023,22(04):379-382.[doi:10.3760/cma.j.cn101785-202201043-015]
儿童后肾腺瘤诊治分析
- Title:
- Clinical features and treatment analysis of metanephric adenoma in children: a series
- Keywords:
- Metanephric Adenoma; Kidney Diseases; Diagnosis; Urologic Surgical Procedures; Pathology; Surgical; Prognosis; Child
- 摘要:
- 目的 探讨儿童后肾腺瘤的临床特点、诊断及治疗方法。方法 以2008年6月至2021年12月首都医科大学附属北京儿童医院泌尿外科收治的8例确诊为后肾腺瘤的患儿为研究对象,收集其临床资料,针对临床特点、影像学检查、手术方式、病理结果及预后进行回顾性分析。结果 8例后肾腺瘤患儿中,男7例,女1例;年龄1岁4个月至10岁4个月,平均年龄5岁7个月;右侧7例,左侧1例;2例因腹痛、1例因腹胀、1例因红细胞增多症经超声检查发现肾脏占位而入院,其余4例均无明显症状。患儿均采取肿瘤切除术,术后恢复良好,随访时间11个月至9年2个月,平均5年7个月,未见肿瘤复发,1例红细胞增多症患儿术后3个月复查红细胞水平恢复至正常。结论 后肾腺瘤临床较罕见,临床表现及影像学检查诊断相对困难,术后病理及免疫组化检查可明确诊断。患儿预后相对较好,术后无需常规化疗,术后3年内应常规行腹部及盆腔影像学检查。
- Abstract:
- Objective To explore the clinical characteristics,diagnoses and treatments of metanephric adenoma in children.Methods From June 2008 to December 2021,8 children were diagnosed as metanephric adenoma.Imaging features,surgical approaches,pathological findings and prognoses were reviewed retrospectively.Results There were 7 boys and 1 girl with an average age of 67(16-124)months.The involved side was right(n=7)and left(n=1).The presenting manifestations were abdominal pain(n=2),distention(n=1),polycythemia(n=1)non-specific(n=4).After tumor resection or nephrectomy,all of them recovered well without recurrence.The average follow-up period was 67(9-110)months.Erythrocyte level of the child with polycythemia normalized within 3 months post-operation.Conclusion As a rare tumor,metanephric adenoma is difficult to be diagnosed due to clinical characteristics and imaging features.It has a relatively favorable prognosis.Immunohistochemical findings are helpful in diagnosis.Chemotherapy is not required after surgery and imaging examinations of abdomen and pelvis should be performed as regularly during 3-year follow-up period.
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备注/Memo
收稿日期:2022-1-20。
通讯作者:张潍平,Email:zhangwpp@163.com