Yang Chao,Wang Shan,Li Changchun,et al.Application of three-dimensional printing technology in vascular skeletal surgery for children with retroperitoneal neuroblastoma[J].Journal of Clinical Pediatric Surgery,2019,18(05):376-380.[doi:10.3969/j.issn.1671-6353.2019.05.008]
3D打印技术在儿童腹膜后神经母细胞瘤血管骨骼化手术中的应用价值探讨
- Title:
- Application of three-dimensional printing technology in vascular skeletal surgery for children with retroperitoneal neuroblastoma
- 关键词:
- 腹膜后肿瘤/外科学; 神经母细胞瘤/外科学; 3D打印; 儿童
- Keywords:
- Betroperitoneal Neoplasms/SU; Neuroblastoma/SU; 3D printing; Child
- 分类号:
- R729;R739.4;R857.3
- 摘要:
- 目的 探讨3D打印技术在儿童腹膜后神经母细胞瘤血管骨骼化手术中的应用价值。方法 以2016年1月至2018年6月重庆医科大学附属儿童医院收治的腹膜后神经母细胞瘤患儿为研究对象，符合入选标准的40例病例根据术前是否进行3D肿瘤模型打印分为3D打印组和非3D打印组。记录肿瘤大小、手术时间、手术切除率、并发症发生率等资料，术后对患儿家属进行问卷调查，并对调查结果进行统计分析。结果 3D打印组共15例，男7例，女8例，平均年龄（40.5±28.6）个月；非3D打印组共25例，男13例，女12例，平均年龄（43.3±24.8）个月。3D模型显示肿瘤与临近脏器、血管间的位置关系清晰。所有患儿均成功接受血管骨骼化肿瘤切除术。两组患儿性别、年龄、肿瘤分期、肿瘤侵犯血管数目、手术切除率、并发症发生率、术后复发及生存率差异均无统计学意义（P>0.05），3D打印组手术用时显著少于非3D打印组（P<0.05），且患儿家属对病情掌握程度明显高于非3D打印组（P<0.05）。结论 3D打印肿瘤模型可清晰显示儿童腹膜后神经母细胞瘤复杂的解剖关系，有利于外科医生进行术前规划，缩短手术时间，并可提高患儿家属对于手术方式的认知及认可程度，有利于增进患儿家属对医生工作的理解和配合。
- Abstract:
- Objective To explore the value of three-dimensional (3D) printing in vascular skeletal surgery for children with retroperitoneal neuroblastoma.Methods From January 2016 to June 2018,hospitalized children with retroperitoneal neuroblastoma fulfilling the inclusion criteria were divided into 3D and non-3D print groups according to whether 3D tumor model was printed preoperatively.Tumor size,operative duration,surgical resection rate and complication rate were recorded.Family members responded to a questionnaire and the results were statistically analyzed.Results For 15 children in 3D printing group,there were 7 boys and 8 girls with an average age of (40.5±28.6) months;for 25 children in non-3D printing group,there were 13 boys and 12 girls with an average age of (43.3±24.8) months.3D model could delineate a distinct relationship between tumor,adjacent organs and blood vessels.All of them successfully underwent vascular skeletal tumor resection.No significant inter-group differences existed in gender,age,tumor stage size,number of tumor invaded vessel,surgical resection rate,complication rate,postoperative recurrence or survival rate (P>0.05).In non-3D printing group (P<0.05),family members’ scores on the degree of disease mastery were significantly higher than those in non-3D printing group (P<0.05).Conclusion 3D printing tumor model can distinctly delineate the complex anatomical relationship of retroperitoneal neuroblastoma in children.And it is conducive for preoperative planning,shortening operative duration and improving the awareness of family members on surgical approaches and patient-physician rapports.
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备注/Memo
收稿日期:2018-10-20。
基金项目:重庆市卫生计生委医学科研计划项目（编号：2016MSXM042），重庆市研究生教育教学改革研究项目（编号：yjg20163022）
通讯作者:杨超,Email:400843@hospital.cqmu.edu.cn