[1]吴书清,钟斌,刘辉,等. Bishop-Koop 造瘘术和双口造瘘术在新生儿坏死性小肠结肠炎中的疗效比较[J].临床小儿外科杂志,2018,17(11):835-839.
　Wu Shuqing,Zhong Bin,Liu Hui,et al. Comparison of therapeutic efficacies of BishopKoop stoma versus double mouth enterostomy for neonatal necrotizing enterocolitis.[J].Journal of Clinical Pediatric Surgery,2018,17(11):835-839.
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 Bishop-Koop 造瘘术和双口造瘘术在新生儿坏死性小肠结肠炎中的疗效比较

《临床小儿外科杂志》[ISSN:1671-6353/CN:43-1380/R] 卷: 第17卷 期数: 2018年11期 页码: 835-839 栏目: 论著 出版日期: 2018-11-20
Title:
 Comparison of therapeutic efficacies of BishopKoop stoma versus double mouth enterostomy for neonatal necrotizing enterocolitis.
作者:
 吴书清; 钟斌; 刘辉; 等.
 赣州市妇幼保健院新生儿外科
Author(s):
 Wu Shuqing; Zhong Bin; Liu Hui; Shu Fang; Liu Chuanrong; Huang Xiuming; Wu Jinhua.
 Department of Neonatal Surgery,Municipal Maternal & Children’s Healthcare Service Centre,Ganzhou 341000,China.
关键词:
 ; 小肠结肠炎;  坏死性;  BishopKoop造瘘术;  新生儿
Keywords:
 ; Enterocolitis;  Necrotizing;  BishopKoop Stoma;  Neonate
文献标志码:
A
摘要:
 目的比较BishopKoop造瘘术和双口造瘘术在新生儿坏死性小肠结肠炎中的应用效果。方法回顾性分析赣州市妇幼保健院2010年至2016年收治的79例行肠造瘘术的新生儿坏死性小肠结肠炎患儿的临床资料，依据手术方式的不同分为双口造瘘组和BishopKoop造瘘组，比较两组患儿的手术治疗效果、二次关瘘手术时间及并发症等。 结果两组患儿的早产比例、低出生体重比例、Bell分期及病情严重程度差异无统计学意义（P>0.05）；高位小肠造瘘的比例BishopKoop组明显高于双口造瘘组，差异有统计学意义（P<0.05）。双口造瘘组治愈28例，死亡16例;BishopKoop组治愈30例， 5例因感染性休克并多器官功能衰竭而死亡;BishopKoop组的病死率明显低于双口造瘘组，差异有统计学意义（P<0.05）。双口造瘘组关瘘手术时间为（87±25）min，BishopKoop组关瘘手术时间为（73±22）min，差异有统计学意义（P<0.05）。双口造瘘组术后短期发现并发症12例次，BishopKoop组术后出现并发症5例次，差异有统计学意义（P<0.05）。 结论新生儿坏死性小肠结肠炎行肠造瘘治疗时，采用BishopKoop造瘘术较传统双口造瘘术更加安全，二次关瘘时间明显缩短，相关并发症少，值得推广应用。
Abstract:
 ObjectiveTo compare the clinical efficacies of small intestine BishopKoop stoma versus double mouth enterostomy for neonatal necrotizing enterocolitis (NEC).MethodsA total of 79 NEC patients undergoing enterostomy from 2010 to 2016 were analyzed retrospectively.They were categorized by operative approaches into two groups of double mouth enterostomy and BishopKoop stoma.The relevant clinical data included operative efficacies,timing of enterostomy closure and complications were compared.ResultsNo significant intergroup difference existed in ratios of preterm infants and low birth weight,Bells staging criteria or disease severity（P＞0.05）.However,the ratio of high small intestinal enterostomy in BishopKoop group was higher than that in double mouth enterostomy group（P＜0.05）.Twentyeight neonates were cured and 16 deaths occurred in double mouth enterostomy group while 30 neonates became cured and there were 5 deaths in BishopKoop stoma group.And the mortality causes were septic shock and multiple organ failure.The mortality rate of BishopKoop stoma group was lower than that of double mouth enterostomy group（P＜0.05）.Significant difference existed in timing of enterostomy closure between double mouth enterostomy group (87±25 min) and BishopKoop stoma group(73±22 min)（P＜0.05）.Five cases had complications in BishopKoop stoma group versus 12 cases in double mouth enterostomy group.ConclusionFor NEC,BishopKoop stoma is safer and more effective than double mouth enterostomy.And there are fewer complications and the time of enterostomy closure is shorter.Wider popularization is recommended.

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更新日期/Last Update: 2018-11-23