SHI Jia,WU Wen-jie,PAN Wei-hua,et al.Clinical treatment and short term fllow-up biliary atresia.[J].Journal of Clinical Pediatric Surgery,2010,9(03):0.
78例胆道闭锁患儿诊疗与近期随访分析
- Title:
- Clinical treatment and short term fllow-up biliary atresia.
- Keywords:
- Biliary Atresia/DI; Biliary Atresia/TH; Follow-up Studies
- 摘要:
- 目的 回顾性分析本院78例胆道闭锁患儿的诊疗经验，探讨胆道闭锁患儿的近期预后及影响近期预后的因素。 方法 2003年1月至2008年12月本院共收治胆道闭锁患儿78例，对其诊疗过程及随访情况进行分析，影响预后的因素采用卡方检验、秩和检验等进行分析，P < 0.05为差异有统计学意义。 结果 黄疸平均发生日龄为（13.00±18.36）d，其中48例行Kasai手术，平均手术日龄为（84.50±34.48）d。中位随访时间为（12.82±11.65）个月。Kasai术后黄疸消退率为45.83%，手术时间< 60 d、60 ～ 90 d、> 90 d的患儿黄疸消退率分别为60.00%、56.67%和15.38%，差异有统计学意义。I、II型胆道闭锁患儿术后黄疸消退率为66.67%，III型胆道闭锁术后黄疸消退率为41.03%，差异无统计学意义。Kasai术后有无胆管炎发生者黄疸消退率分别为40.91%、50.00%，差异无统计学意义。病毒感染、先天性畸形及术前应用中药退黄治疗对预后无显著影响。 结论 提高胆道闭锁的疗效是小儿外科的一大难题，手术日龄是决定Kasai手术短期预后的关键因素。
- Abstract:
- Objective Review the treatment of biliary atresia, to determine the short term outcome of biliary atresia and the prognostic factors. Methods The records of 78 patients with biliary atresia in Xinhua Hospital between January 2003 and December 2008 were an
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备注/Memo
作者单位：中国医科大学附属盛京医院小儿骨科（辽宁省沈阳市，110004），E-mail：websyy@tom.com