Qi Yanwei,Sun Huiyuan,Zhang Wenhui,et al.Left-sided renal immature teratoma in neonates:one case report[J].Journal of Clinical Pediatric Surgery,2026,(03):289-292.[doi:10.3760/cma.j.cn101785-20251119-00068]
新生儿左侧肾脏未成熟畸胎瘤1例
- Title:
- Left-sided renal immature teratoma in neonates:one case report
- 摘要:
- 本文报道1例25天女婴左侧肾脏未成熟畸胎瘤病例。患儿因腹部肿物入院,伴重度贫血,影像学提示左肾巨大占位,穿刺病理考虑畸胎性肿瘤。经多学科会诊讨论后,予术前纠正贫血、抗感染等准备,全身麻醉下行左侧肾脏肿瘤完整切除术,术中处理脾脏血管受压等情况。术后病理确诊为2级未成熟畸胎瘤,未行化疗,经5年随访,患儿无肿瘤复发,脾脏功能恢复正常,预后良好。
参考文献/References:
[1] Guntiboina VA, Islam N, Banerjee S, et al.Post therapy Wilms tumour or ectopic immature renal tissue:a pathologist’s diagnostic dilemma[J].Indian J Pathol Microbiol, 2019, 62(2):266-269.DOI:10.4103/IJPM.IJPM_112_18.
[2] Chu H, Deng QF, Liu X, et al.Kidney teratoma:a case report and literature review[J].Urol Case Rep, 2018, 20:83-84.DOI:10.1016/j.eucr.2018.07.012.
[3] Albany C, Einhorn LH.Extragonadal germ cell tumors:clinical presentation and management[J].Curr Opin Oncol, 2013, 25(3):261-265.DOI:10.1097/CCO.0b013e32835f085d.
[4] Bokemeyer C, Nichols CR, Droz JP, et al.Extragonadal germ cell tumors of the mediastinum and retroperitoneum:results from an international analysis[J].J Clin Oncol, 2002, 20(7):1864-1873.DOI:10.1200/JCO.2002.07.062.
[5] Motzer RJ, Amsterdam A, Prieto V, et al.Teratoma with malignant transformation:diverse malignant histologies arising in men with germ cell tumors[J].J Urol, 1998, 159(1):133-138.DOI:10.1016/s0022-5347(01)64035-7.
[6] 张崔建, 杨新宇, 李学松, 等.肾脏非成熟囊性畸胎瘤一例报道及文献回顾[J].中华临床医师杂志(电子版), 2010, 4(12):2563-2566.DOI:10.3877/cma.j.issn.1674-0785.2010.12.042. Zhang CJ, Yang XY, Li XS, et al.Report of a case of immature cystic teratoma of the kidney and review of the literature[J].Chin J Clin (Electronic Edition), 2010, 4(12):2563-2566.DOI:10.3877/cma.j.issn.1674-0785.2010.12.042.
[7] Sigumonrong YH, Putra AA.Renal immature teratoma in infant:a rare case report[J].Urol Case Rep, 2025, 59:102967.DOI:10.1016/j.eucr.2025.102967.
[8] Liu YC, Wang JS, Chen CJ, et al.Intrarenal mixed germ cell tumor[J].J Urol, 2000, 164(6):2020-2021.DOI:10.1097/00005392-200012000-00039.
[9] 康子明, 王城, 张彪, 等.成人肾盂畸胎瘤1例[J].临床泌尿外科杂志, 2025, 40(4):382-386.DOI:10.13201/j.issn.1001-1420.2025.04.018. Kang ZM, Wang C, Zhang B, et al.One case report of renal pelvic teratoma in adult[J].J Clin Urol, 2025, 40(4):382-386.DOI:10.13201/j.issn.1001-1420.2025.04.018.
[10] 李俊龙, 章小龙, 徐刚, 等.原发性肾非成熟性畸胎瘤1例报告[J].中华泌尿外科杂志, 2022, 43(3):219-220.DOI:10.3760/cma.j.cn112330-20210126-00049. Li JL, Zhang XL, Xu G, et al.Primary renal immature teratoma:one case report[J].Chin J Urol, 2022, 43(3):219-220.DOI:10.3760/cma.j.cn112330-20210126-00049.
[11] Al Sharqi A, Mouaffak S, Al Rahbi F, et al.Primary immature renal teratoma in a neonate[J].Oman Med J, 2023, 38(5):e558.DOI:10.5001/omj.2023.49.
[12] Ronchi A, Cozzolino I, Montella M, et al.Extragonadal germ cell tumors:not just a matter of location.A review about clinical, molecular and pathological features[J].Cancer Med, 2019, 8(16):6832-6840.DOI:10.1002/cam4.2195.
[13] Beckwith JB.Wilms’ tumor and other renal tumors of childhood:a selective review from the National Wilms’ Tumor Study Pathology Center[J].Hum Pathol, 1983, 14(6):481-492.DOI:10.1016/s0046-8177(83)80003-3.
[14] Idrissi-Serhrouchni K, El-Fatemi H, El madi A, et al.Primary renal teratoma:a rare entity[J].Diagn Pathol, 2013, 8:107.DOI:10.1186/1746-1596-8-107.
[15] Geethamani V, Kusuma V, Gowda KMS, et al.Adult Wilms’ tumour:a case report with review of literature[J].Diagn Pathol, 2006, 1:46.DOI:10.1186/1746-1596-1-46.
[16] Hamidi H, Foladi N.Intrarenal teratoma within a horseshoe kidney-a case report[J].Radiol Case Rep, 2020, 15(10):1743-1746.DOI:10.1016/j.radcr.2020.07.013.
[17] 杨婷, 王珊, 胡显良.32例小儿未成熟畸胎瘤临床诊疗特点回顾分析[J].中国小儿血液与肿瘤杂志, 2015, 20(5):245-250.DOI:10.3969/j.issn.1673-5323.2015.05.006. Yang T, Wang S, Hu XL.Retrospective study of clinical features of immature teratoma in young children:a report of 32 cases[J].J China Pediatr Blood Cancer, 2015, 20(5):245-250.DOI:10.3969/j.issn.1673-5323.2015.05.006.
[18] 姚强华, 汤静燕, 潘慈, 等.儿童Ⅳ期颅外恶性生殖细胞肿瘤疗效观察[J].临床儿科杂志, 2017, 35(5):321-324.DOI:10.3969/j.issn.1000-3606.2017.05.001. Yao QH, Tang JY, Pan C, et al.Study on the clinical outcomes of children with stage Ⅳ malignant extracranial germ cell tumors[J].J Clin Pediatr, 2017, 35(5):321-324.DOI:10.3969/j.issn.1000-3606.2017.05.001.
相似文献/References:
[1]彭斌,顾志成,吴缤,等.20例小儿骶尾部畸胎瘤诊断分析[J].临床小儿外科杂志,2008,7(02):30.
[2]田琪 董亮 王晓晔 崔华雷. 腹腔镜在小儿卵巢良性畸胎瘤手术中的应用[J].临床小儿外科杂志,2011,10(04):258.
[J].Journal of Clinical Pediatric Surgery,2011,10(03):258.
[3]何小庆 王珊 刘苗.婴儿畸胎瘤甲胎蛋白量化检测的临床意义探讨[J].临床小儿外科杂志,2014,13(02):91.
[4]姚祥,王珊,何小庆,等. 399例儿童畸胎瘤的单中心临床诊疗分析[J].临床小儿外科杂志,2016,15(03):241.
[5]严 萍 徐亚娟 路长贵 唐维兵.新生儿骶尾部畸胎瘤术后肛门直肠功能随访[J].临床小儿外科杂志,2018,17(01):13.
Yan Ping,Xu Yajuan,Lu Changgui,et al.Anorectal Function after Sacrococcygeal Teratoma surgery in the Neonate: a Post-operative Follow-up study[J].Journal of Clinical Pediatric Surgery,2018,17(03):13.
[6]黄振强,唐华建,郑锦涛,等.腹腔镜辅助手术切除小儿骶尾部畸胎瘤的疗效分析[J].临床小儿外科杂志,2018,17(08):607.
Huang Zhenqiang,Tang Huajiang,Zheng Jintao,et al.Efficacy and feasibility of laparoscopic assisted resection of sacrococcygeal teratoma in children.[J].Journal of Clinical Pediatric Surgery,2018,17(03):607.
[7]罗真东,郑曼娜,李嘉豪,等.儿童腹膜后畸胎瘤围手术期并发症的危险因素分析[J].临床小儿外科杂志,2020,19(04):347.[doi:10.3969/j.issn.1671-6353.2020.04.013]
Luo Zhendong,Zheng Manna,Li Jiahao,et al.Risk factors for perioperative complications of pediatric retroperitoneal teratoma[J].Journal of Clinical Pediatric Surgery,2020,19(03):347.[doi:10.3969/j.issn.1671-6353.2020.04.013]
[8]程伶熙,杨星海,林松,等.腹膜后寄生胎7例及文献回顾[J].临床小儿外科杂志,2021,20(10):956.[doi:10.12260/lcxewkzz.2021.10.012]
Cheng Lingxi,Yang Xinghai,Lin Song,et al.Retroperitoneal fetus-in-fetu: a report of 7 cases with a literature review[J].Journal of Clinical Pediatric Surgery,2021,20(03):956.[doi:10.12260/lcxewkzz.2021.10.012]
[9]赵杭燕,诸纪华,王金湖,等.胎儿巨大骶尾部畸胎瘤宫外产时处理1例[J].临床小儿外科杂志,2022,21(11):1098.[doi:10.3760/cma.j.cn101785-202201032-019]
Zhao Hangyan,Zhu Jihua,Wang Jinhu,et al.A case report of fetal giant sacrococcygeal teratoma during exutero intrapartum treatment[J].Journal of Clinical Pediatric Surgery,2022,21(03):1098.[doi:10.3760/cma.j.cn101785-202201032-019]
[10]高婷婷,徐伟珏,吕志宝,等.儿童骶尾部畸胎瘤预后相关因素分析[J].临床小儿外科杂志,2023,22(01):62.[doi:10.3760/cma.j.cn101785-202008060-012]
Gao Tingting,Xu Weijue,Lyu Zhibao,et al.Correlation prognostic analysis of sacrococcygeal teratoma in children[J].Journal of Clinical Pediatric Surgery,2023,22(03):62.[doi:10.3760/cma.j.cn101785-202008060-012]
备注/Memo
收稿日期:2025-11-19。
基金项目:河北省政府资助临床医学优秀人才培养项目(ZF2026296)
通讯作者:仲智勇,Email:hbydmike99@163.com