Liu Yanhan,Xu Hongwen.Research advances on using pMRI for predicting avascular necrosis after closed reduction in developmental dislocation of the hip[J].Journal of Clinical Pediatric Surgery,2025,(10):991-994.[doi:10.3760/cma.j.cn101785-202409064-016]
钆增强灌注磁共振预测发育性髋关节脱位闭合复位后股骨头坏死的研究进展
- Title:
- Research advances on using pMRI for predicting avascular necrosis after closed reduction in developmental dislocation of the hip
- 关键词:
- 发育性髋关节发育不良; 股骨头坏死; 磁共振血管造影术; 预测
- Keywords:
- Developmental Dysplasia of the Hip; Femur Head Necrosis; Magnetic Resonance Angiography; Forecasting
- 摘要:
- 发育性髋关节脱位(developmental dislocation of the hip,DDH)是常见的儿童下肢先天性畸形之一。目前,全身麻醉下闭合复位、人位石膏固定是6~24月龄DDH患儿的首选治疗方法,而股骨头缺血性坏死(avascular necrosis,AVN)是DDH闭合复位后的主要并发症之一。有证据表明,DDH闭合复位后行钆增强灌注磁共振(gadolinium-enhanced perfusion MRI,pMRI)检查可以为外科医师提供股骨头血流灌注及信号改变的数据。早期发现髋关节复位时的缺血,可能可以预测AVN的后期发展,将是进一步研究修改当前治疗方法或创造新治疗方法的基础。本文就pMRI预测DDH闭合复位后AVN发生的研究进展进行综述。
- Abstract:
- Developmental dislocation of the hip (DDH) is one of the most common congenital deformities of the lower limbs in children.Currently,closed reduction under general anesthesia followed by spica cast fixation is the first-line treatment for DDH in children aged 6 to 24 months.However,avascular necrosis (AVN) of the femoral head remains a major complication following closed reduction.There is a growing evidence that gadolinium-enhanced perfusion magnetic resonance imaging (pMRI) after closed reduction can provide valuable data regarding femoral head blood perfusion and signal alterations.Early detection of ischemia during reduction may allow for prediction of AVN development,which could form the basis for further modifications to current treatment protocols or the development of new therapeutic approaches.This review summarizes recent advances in the use of pMRI for predicting AVN following closed reduction of DDH.
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备注/Memo
收稿日期:2024-9-25。
基金项目:国家自然科学基金(82402179)
通讯作者:徐宏文,Email:gzorthopedics@qq.com