[1]杨伊帆,李祥,郭芳,等.儿童涎腺黏液表皮样癌一例并文献综述[J].临床小儿外科杂志,2024,(08):777-780.[doi:10.3760/cma.j.cn101785-202304035-014]
　Yang Yifan,Li Xiang,Guo Fang,et al.Mucoepidermoid carcinoma of salivary gland in children:one case report with a literature review[J].Journal of Clinical Pediatric Surgery,2024,(08):777-780.[doi:10.3760/cma.j.cn101785-202304035-014]
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儿童涎腺黏液表皮样癌一例并文献综述

《临床小儿外科杂志》[ISSN:1671-6353/CN:43-1380/R] 卷: 期数: 2024年08 页码: 777-780 栏目: 临床研究与实践 出版日期: 2024-08-01
Title:
Mucoepidermoid carcinoma of salivary gland in children:one case report with a literature review
作者:
杨伊帆1;  李祥1;  郭芳2;  薛磊1;  刘召明1
1. 河北省儿童医院整形外科, 石家庄 050031;
2. 河北省儿童医院感染科, 石家庄 050031
Author(s):
Yang Yifan1;  Li Xiang1;  Guo Fang2;  Xue Lei1;  Liu Zhaoming1
1. Department of Plastic Surgery, Hebei Children’s Hospital, Shijiazhuang 050031, China;
2. Department of Infection Diseases, Hebei Children’s Hospital, Shijiazhuang 050031, China
关键词:
涎腺肿瘤; 癌;  黏液表皮样; 诊断; 治疗; 儿童
Keywords:
Salivary Gland Neoplasms; Carcinoma;  Mucoepidermoid; Diagnosis; Therapy; Child
DOI:
10.3760/cma.j.cn101785-202304035-014
摘要:
目的 探讨涎腺黏液表皮样癌的治疗及预后。 方法 回顾性分析河北省儿童医院收治的1例涎腺黏液表皮样癌患儿临床资料。同时以"儿童""涎腺"和"黏液表皮样癌"为检索词在中国知网、万方医学网,以"children""salivary gland"和"mucoepidermoid carcinoma"为检索词在PubMed数据库,未限定时间检索相关文献。按照一定纳入和排除标准筛选文献后进行文献复习。 结果 本例患儿行肿物切除+周围淋巴结摘除手术治疗,持续随访2年无复发,外观恢复良好,未见肿瘤转移。收集符合条件英文文献共报道原发涎腺黏液表皮样癌4例,2例行腮腺浅表切除术,其中1例切缘阳性,5个月后行二次手术及颈部淋巴结清扫;另外2例行全腮腺切除术,保留面神经。随诊无一例复发。 结论 涎腺黏液表皮样癌临床表现缺乏特异性,治疗以手术为主;若切缘及淋巴结阴性,则规律随访即可。
Abstract:
Objective To explore the clinical features,imaging findings,treatments and outcomes of mucoepidermoid carcinoma of salivary gland.Methods Retrospective analysis was conducted for the clinical data of one child with mucoepidermoid carcinoma of salivary gland.A literature review was conducted based upon the searching results of China National Knowledge Infrastructure (CNKI),Wanfang and PubMed databases using such keywords as "children","salivary gland" and "mucoepidermoid carcinoma" without a time limit after excluding some items according to the inclusion criteria.And the relevant literature was reviewed.Results Tumor and peripheral lymph node were removed.During 2-year follow-ups,there was no recurrence,appearance recovery was decent and no tumor metastasis was noted.A total of 4 cases of primary salivary gland mucoepidermoid carcinoma were retrieved as eligible English literature.Among 2 cases of superficial parotid excision,one child of positive incisional margin underwent re-operation and neck lymph node dissection 5 months later.Another two underwent total parotidectomy with a preservation of facial nerve.There was no recurrence during follow-ups.Conclusions Mucoepidermoid carcinoma of salivary gland is a rare malignant tumor of head and neck.Its clinical manifestations are generally non-specific.Surgery remains a major treatment and regular follow-ups are sufficient if margins and lymph nodes are negative.

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备注/Memo

收稿日期:2023-4-13。
基金项目:河北省医学科学研究课题计划(20200641)
通讯作者:刘召明,Email:15833917213@163.com

更新日期/Last Update: 1900-01-01