[1]赖名耀,李少群,李娟,等.再程放疗联合CDK4/6抑制剂治疗儿童复发弥漫内生型脑桥胶质瘤的真实世界研究[J].临床小儿外科杂志,2024,(05):440-445.[doi:10.3760/cma.j.cn101785-202310016-008]
 Lai Mingyao,Li Shaoqun,Li Juan,et al.A real-world study of reirradiation plus CDK4/6 inhibitors in treating recurrent pediatric diffuse intrinsic pontine glioma[J].Journal of Clinical Pediatric Surgery,2024,(05):440-445.[doi:10.3760/cma.j.cn101785-202310016-008]
点击复制

再程放疗联合CDK4/6抑制剂治疗儿童复发弥漫内生型脑桥胶质瘤的真实世界研究

参考文献/References:

[1] Ostrom QT,Patil N,Cioffi G,et al.CBTRUS statistical report:primary brain and other central nervous system tumors diagnosed in the United States in 2013-2017[J].Neuro Oncol,2020,22(12 Suppl 2):iv1-iv96.DOI:10.1093/neuonc/noaa200.
[2] Hargrave D,Bartels U,Bouffet E.Diffuse brainstem glioma in children:critical review of clinical trials[J].Lancet Oncol,2006,7(3):241-248.DOI:10.1016/S1470-2045(06)70615-5.
[3] Kim HJ,Suh CO.Radiotherapy for diffuse intrinsic pontine glioma:insufficient but indispensable[J].Brain Tumor Res Treat,2023,11(2):79-85.DOI:10.14791/btrt.2022.0041.
[4] Kim HJ,Lee JH,Kim Y,et al.Suggestions for escaping the dark ages for pediatric diffuse intrinsic pontine glioma treated with radiotherapy:analysis of prognostic factors from the national multicenter study[J].Cancer Res Treat,2023,55(1):41-49.DOI:10.4143/crt.2021.1514.
[5] Paugh BS,Broniscer A,Qu CX,et al.Genome-wide analyses identify recurrent amplifications of receptor tyrosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma[J].J Clin Oncol,2011,29(30):3999-4006.DOI:10.1200/JCO.2011.35.5677.
[6] Duchatel RJ,Jackson ER,Alvaro F,et al.Signal transduction in diffuse intrinsic pontine glioma[J].Proteomics,2019,19(21/22):e1800479.DOI:10.1002/pmic.201800479.
[7] Buczkowicz P,Hoeman C,Rakopoulos P,et al.Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations[J].Nat Genet,2014,46(5):451-456.DOI:10.1038/ng.2936.
[8] Matthews HK,Bertoli C,de Bruin RAM.Cell cycle control in cancer[J].Nat Rev Mol Cell Biol,2022,23(1):74-88.DOI:10.1038/s41580-021-00404-3.
[9] Sun Y,Sun Y,Yan K,et al.Potent anti-tumor efficacy of palbociclib in treatment-na?ve H3.3K27M-mutant diffuse intrinsic pontine glioma[J].E Bio Medicine,2019,43:171-179.DOI:10.1016/j.ebiom.2019.04.043.
[10] Farrukh S,Habib S,Rafaqat A,et al.Emerging therapeutic strategies for diffuse intrinsic pontine glioma:a systematic review[J].Healthcare (Basel),2023,11(4):559.DOI:10.3390/healthcare11040559.
[11] Hayden E,Holliday H,Lehmann R,et al.Therapeutic targets in diffuse midline gliomas-an emerging landscape[J].Cancers (Basel),2021,13(24):6251.DOI:10.3390/cancers13246251.
[12] Hashizume R,Zhang A,Mueller S,et al.Inhibition of DNA damage repair by the CDK4/6 inhibitor palbociclib delays irradiated intracranial atypical teratoid rhabdoid tumor and glioblastoma xenograft regrowth[J].Neuro Oncol,2016,18(11):1519-1528.DOI:10.1093/neuonc/now106.
[13] Guerini AE,Pedretti S,Salah E,et al.A single-center retrospective safety analysis of cyclin-dependent kinase 4/6 inhibitors concurrent with radiation therapy in metastatic breast cancer patients[J].Sci Rep,2020,10(1):13589.DOI:10.1038/s41598-020-70430-2.
[14] Chavaz L,Janssens GO,Bolle S,et al.Neurological symptom improvement after re-irradiation in patients with diffuse intrinsic pontine glioma:a retrospective analysis of the SIOP-E-HGG/DIPG project[J].Front Oncol,2022,12:926196.DOI:10.3389/fonc.2022.926196.
[15] Amsbaugh MJ,Mahajan A,Thall PF,et al.A phase 1/2 trial of reirradiation for diffuse intrinsic pontine glioma[J].Int J Radiat Oncol Biol Phys,2019,104(1):144-148.DOI:10.1016/j.ijrobp.2018.12.043.
[16] Chi AS,Tarapore RS,Hall MD,et al.Pediatric and adult H3 K27M-mutant diffuse midline glioma treated with the selective DRD2 antagonist ONC201[J].J Neurooncol,2019,145(1):97-105.DOI:10.1007/s11060-019-03271-3.
[17] Majzner RG,Ramakrishna S,Yeom KW,et al.GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas[J].Nature,2022,603(7903):934-941.DOI:10.1038/s41586-022-04489-4.
[18] Gállego Pérez-Larraya J,Garcia-Moure M,Labiano S,et al.Oncolytic DNX-2401 virus for pediatric diffuse intrinsic pontine glioma[J].N Engl J Med,2022,386(26):2471-2481.DOI:10.1056/NEJMoa2202028.
[19] 张力伟.脑干胶质瘤张力伟2020观点[M].北京:科学技术文献出版社,2019. Zhang LW.Brainstem glioma:2020 viewpoint of Zhang Liwei [M].Beijing:Science and Technology Literature Publishing House,2019.
[20] Tinkle CL,Campbell K,Han YY,et al.Radiation dose response of neurologic symptoms during conformal radiotherapy for diffuse intrinsic pontine glioma[J].J Neurooncol,2020,147(1):195-203.DOI:10.1007/s11060-020-03415-w.
[21] 赖名耀,李少群,李娟,等.放疗联合替莫唑胺治疗儿童弥漫内生型脑桥胶质瘤的疗效分析[J].中华神经外科杂志,2022,38(7):669-673.DOI:10.3760/cma.j.cn112050-20220225-00112. Lai MY,Li SQ,Li J,et al.Efficacy of radiotherapy plus temozolomide in the treatment of pediatric diffuse intrinsic pontine glioma[J].Chin J Neurosurg,2022,38(7):669-673.DOI:10.3760/cma.j.cn112050-20220225-00112.
[22] Hoffman LM,Veldhuijzen van Zanten SEM,Colditz N,et al.Clinical,radiologic,pathologic,and molecular characteristics of long-term survivors of diffuse intrinsic pontine glioma (DIPG):a collaborative report from the international and European society for pediatric oncology DIPG registries[J].J Clin Oncol,2018,36(19):1963-1972.DOI:10.1200/JCO.2017.75.9308.
[23] Yang Z,Sun L,Chen HB,et al.New progress in the treatment of diffuse midline glioma with H3K27M alteration[J].Heliyon,2024,10(2):e24877.DOI:10.1016/j.heliyon.2024.e24877.
[24] DeWire M,Fuller C,Hummel TR,et al.A phase Ⅰ/Ⅱ study of ribociclib following radiation therapy in children with newly diagnosed diffuse intrinsic pontine glioma (DIPG)[J].J Neurooncol,2020,149(3):511-522.DOI:10.1007/s11060-020-03641-2.
[25] DeWire M,Lazow M,Campagne O,et al.Phase Ⅰ study of ribociclib and everolimus in children with newly diagnosed DIPG and high-grade glioma:a CONNECT pediatric neuro-oncology consortium report[J].Neurooncol Adv,2022,4(1):vdac055.DOI:10.1093/noajnl/vdac055.

备注/Memo

收稿日期:2023-10-10。
基金项目:广州市科技计划项目(202201011741)
通讯作者:蔡林波,Email:cailinbo999@163.com

更新日期/Last Update: 1900-01-01