Tian Yanjun,Su Zeli,Xing Xinran,et al.Prediction of testicular activity by platelet distribution width in children with testicular torsion[J].Journal of Clinical Pediatric Surgery,2023,22(10):961-965.[doi:10.3760/cma.j.cn101785-202211015-011]
血小板分布宽度对睾丸扭转患儿睾丸活性的预测作用研究
- Title:
- Prediction of testicular activity by platelet distribution width in children with testicular torsion
- 摘要:
- 目的 探讨术前血液学指标对睾丸扭转患儿睾丸活性的预测价值。方法 本研究为回顾性研究。以宁夏医科大学总医院小儿外科2011年1月至2022年6月收治的66例睾丸扭转患儿为研究对象,收集患儿发病时长、术前血液学参数及睾丸扭转度数,根据术中是否切除扭转睾丸将患儿分为睾丸复位固定术组(21例)和睾丸切除术组(45例),比较两组患儿病程时长、睾丸扭转度数和术前血液学指标的差异,进行单因素分析。将单因素分析中有统计学意义的变量纳入多因素Logistic回归分析,对多因素分析中存在统计学意义的指标进行受试者工作特征(receiver operating characteristic,ROC)曲线分析。结果 单因素分析显示,两组患儿病程时长、睾丸扭转度数、平均血小板体积(mean platelet volume,MPV)和血小板分布宽度(platelet distribution width,PDW)比较,差异有统计学意义(P<0.05)。多因素Logistic回归分析结果显示,病程时长(OR=1.032,95%CI:1.011~1.055,P=0.003)、睾丸扭转度数(OR＝1.006,95%CI:1.002~1.005,P=0.003)和PDW(OR＝3.318,95%CI:1.004~9.749,P=0.049)是睾丸切除的独立危险因素。患儿病程时长、睾丸扭转度数和PDW预测睾丸坏死的ROC曲线下面积分别为0.786、0.745和0.728。结论 睾丸扭转患儿术前PDW参数可作为评估扭转睾丸是否存在活性以及是否需要行扭转睾丸切除的预测指标。
- Abstract:
- Objective To explore the values of hematological parameters in predicting testicular activity in children with testicular torsion (TT).Methods The relevant clinical data were retrospectively reviewed for 66 TT children at Department of Pediatric Surgery from 2011 to 2022.According to actual operative procedures,they were assigned into two groups of reduction & fixation (n=21) and orchiectomy (n=45).The inter-group differences in course of disease,degree of TT and preoperative hematological parameters were compared.The variables with statistical differences in univariate analysis were included for multivariate Logistic analysis.And the parameters with statistical differences in factorial analysis were examined by receiver operating characteristic (ROC) curve.Results According to univariate analysis,significant inter-group differences existed in course of disease,TT,mean platelet volume (MPV) and platelet distribution width (PDW).In multivariate Logistic regression analysis,the duration of disease (OR=1.032,95%CI:1.011-1.055),testicular torsion (OR=1.006,95%CI:1.002-1.005) and PDW (OR=3.318,95%CI:1.004-9.749,0.049) were correlated positively with orchiectomy.ROC curves of course of disease,TT and PDW were analyzed.Area under the curve (AUC) was 0.651,0.745 and 0.681 respectively.Conclusion Preoperative PDW may be utilized as a predictive index for evaluating the activity of TT in children.
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相似文献/References:
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Diagnosis and treatment of neonatal testicular torsion.. Diagnosis and treatment of neonatal testicular torsion.[J].Journal of Clinical Pediatric Surgery,2018,17(10):943.
备注/Memo
收稿日期:2022-11-7。
基金项目:宁夏回族自治区重点研发计划(2021BEG02043)
通讯作者:杜勇,Email:niniduy@126.com