Wang Junjie,He Qiuming,Zhong Wei,et al.Programmed management of H-type congenital tracheoesophageal fistula[J].Journal of Clinical Pediatric Surgery,2023,22(04):340-344.[doi:10.3760/cma.j.cn101785-202303015-008]
H型先天性食管气管瘘的程序化诊治
- Title:
- Programmed management of H-type congenital tracheoesophageal fistula
- Keywords:
- Esophageal Atresia; Tracheoesophageal Fistula; Diagnosis; Surgical Procedures; Operative; Treatment Outcome
- 摘要:
- 目的 总结程序化诊治H型先天性食管气管瘘(H-type tracheoesophageal fistula,H-TEF)的临床效果。方法 回顾性分析2017年3月至2022年3月广州市妇女儿童医疗中心新生儿外科收治的10例采取程序化诊治的H-TEF患儿临床资料。其中新生儿6例,主要表现为反复出现喂养后呛咳;婴幼儿4例,主要表现反复发生肺炎。合并先天性心脏病1例,胸椎半椎体畸形1例。程序化诊治流程:经食管造影和(或)纤维支气管镜检查明确诊断后置入鼻胃管喂养;待炎症指标正常或接近正常,X线胸片肺部无炎性改变后,于术前纤维支气管镜引导下在食管气管瘘管内留置导管;经床边X线检查确认瘘管位置,如瘘管位于第2胸椎水平以上则采取经颈部手术、位于第2胸椎水平以下则采取经胸腔镜手术。结果 10例中,经食管造影确诊7例,经纤维支气管镜确诊3例。患儿术前均成功放置食管气管瘘管内导管。7例瘘管位于第2胸椎水平以上,采取经右颈开放下食管气管瘘修补术;3例瘘管位于第2胸椎水平以下,采取胸腔镜手术。均于术后次日即经鼻胃管喂养,术后1周予食管造影检查,无一例出现吻合口漏或食管气管瘘复发。随访8个月至5年,3例经颈部开放手术患儿出现声音嘶哑,于术后1~6个月恢复;无一例出现吞咽困难、食管气管瘘复发表现。结论 程序化诊治H-TEF可获得满意的临床疗效,为H-TEF的管理提供了一种整体化思路。
- Abstract:
- Objective To summarize the clinical efficacy of programmed management for H-type congenital tracheoesophageal fistula (H-TEF).Methods From March 2017 to March 2022,clinical data were retrospectively reviewed for 10 H-TEF children under programmed management.Six neonates developed recurrent cough after feeding and 4 infants had recurrent pneumonia.One case was associated with congenital heart disease and another had hemivertebra deformity of thoracic vertebra.After a definite diagnosis was confirmed by esophagography and/or fiberbronchoscope,gastric tube feeding was initiated.After inflammatory parameters normalized completely or partially and pneumonic change disappeared on chest film,a catheter was placed in fistula under a guidance of fiberbronchoscope.The position of fistula was confirmed by bedside radiography;H-TEF was repair through a cervical approach when fistula was located above T2 level and thoracoscopically below T2.Results Seven cases were confirmed by esophagography and 3 cases by fiberbronchoscope.Catheter was successfully deployed in fistula in all cases before surgery.Seven cases of fistula above T2 were repaired through a right cervical route and 3 cases of fistula below T2 underwent thoracoscopy.Feeding through a gastric tube resumed the next day and esophagography 1 week later.There was no leakage or recurrence during a follow-up period of (8-60) month.Three cases of hoarseness occurred after cervical surgery and recovered at (1-6) month.No dysphagia or recurrence was noted.Conclusion An integrated strategy for H-TEF yields satisfactory outcomes under programmed management.
参考文献/References:
[1] van Lennep M,Singendonk MMJ,Dall’Oglio L,et al.Oesophageal atresia[J].Nat Rev Dis Primers,2019,5(1):26.DOI:10.1038/s41572-019-0077-0.
[2] Nakazawa S,Yajima T,Shirabe K.Congenital tracheoesophageal fistula in an adult[J].Am J Respir Crit Care Med,2021,203(7):e27-e28.DOI:10.1164/rccm.202003-0689IM.
[3] 温洋,彭芸,翟仁友,等.小儿先天性H型气管食管瘘的诊断[J].医学影像学杂志,2012,22(10):1665-1669.DOI:10.3969/j.issn.1006-9011.2012.10.022. Wen Y,Peng Y,Zhai RY,et al.Diagnosis of congenital H-type tracheoesophageal fistula in infants[J].J Med Imaging,2012,22(10):1665-1669.DOI:10.3969/j.issn.1006-9011.2012.10.022.
[4] Al-Salem AH,Mohaidly MA,Al-Buainain HMH,et al.Congenital H-type tracheoesophageal fistula:a national multicenter study[J].Pediatr Surg Int,2016,32(5):487-491.DOI:10.1007/s00383-016-3873-6.
[5] Taghavi K,Tan Tanny SP,Hawley A,et al.H-type congenital tracheoesophageal fistula:insights from 70 years of The Royal Children’s Hospital experience[J].J Pediatr Surg,2021,56(4):686-691.DOI:10.1016/j.jpedsurg.2020.06.048.
[6] He QM,Ou XX,Lin JH,et al.Flexible endoscopic identification and catheterization of congenital H-type tracheoesophageal fistula using a laryngeal mask[J].Dig Endosc,2022,34(1):228-233.DOI:10.1111/den.14115.
[7] Yang S,Yang RZ,Ma XF,et al.Detail correction for Gross classification of esophageal atresia based on 434 cases in China[J].Chin Med J (Engl),2021,135(4):485-487.DOI:10.1097/CM9.0000000000001673.
[8] Karnak I,Senocak ME,Hi?s?nmez A,et al.The diagnosis and treatment of H-type tracheoesophageal fistula[J].J Pediatr Surg,1997,32(12):1670-1674.DOI:10.1016/s0022-3468(97)90503-0.
[9] Tiwari C,Nagdeve N,Saoji R,et al.Congenital H-type tracheo-oesophageal fistula:an institutional review of a 10-year period[J].J Mother Child,2021,24(4):2-8.DOI:10.34763/jmotherandchild.20202404.d-20-00004.
[10] 何静波,段星星,李皓,等.超声诊断先天性食管闭锁并气管食管瘘的初步探讨[J].临床小儿外科杂志,2012,11(2):109-111.DOI:10.3969/j.issn.1671-6353.2012.02.010. He JB,Duan XX,Li H,et al.Preliminary experience of ultrasonography in the diagnosis of congenital esophagealatresia and tracheoesophageal fistula[J].J Clin Ped Sur,2012,11(2):109-111.DOI:10.3969/j.issn.1671-6353.2012.02.010.
[11] Gunlemez A,Anik Y,Elemen L,et al.H-type tracheoesophageal fistula in an extremely low birth weight premature neonate:appearance on magnetic resonance imaging[J].J Perinatol,2009,29(5):393-395.DOI:10.1038/jp.2008.198.
[12] Lee DY,Kim KM,Kim JS.H-type tracheoesophageal fistula detected by radionuclide salivagram[J].Nucl Med Mol Imaging,2012,46(3):227-229.DOI:10.1007/s13139-012-0148-6.
[13] Moretó M,Gabilondo J,Fernandez-Samaniego F.Treatment of a congenital esophageal fistula by injection of autologous fat[J].Endoscopy,2014,46(Suppl 1):E54-E55.DOI:10.1055/s-0033-1359117.
[14] 殷勇,蒋丽蓉,严志龙,等.支气管镜在儿童气管食管瘘全程手术管理中的应用研究[J].临床儿科杂志,2009,27(1):33-38.DOI:10.3969/j.issn.1000-3606.2009.01.009. Yin Y,Jiang LR,Yan ZL,et al.Application of bronchoscope for surgical management of tracheoesophageal fistula in children[J].J Clin Pediatr,2009,27(1):33-38.DOI:10.3969/j.issn.1000-3606.2009.01.009.
[15] Garcia NM,Thompson JW,Shaul DB.Definitive localization of isolated tracheoesophageal fistula using bronchoscopy and esophagoscopy for guide wire placement[J].J Pediatr Surg,1998,33(11):1645-1647.DOI:10.1016/s0022-3468(98)90599-1.
[16] 孔赤寰,李龙,李颀,等.小儿气管食管瘘手术治疗分析[J].临床小儿外科杂志,2014,13(5):381-383.DOI:10.3969/j.issn.1671-6353.2014.05.004. Kong CH,Li L,Li Q,et al.Surgical treatment of tracheal-esophageal fistula in children[J].J Clin Ped Sur,2014,13(5):381-383.DOI:10.3969/j.issn.1671-6353.2014.05.004.
[17] 孟昭辉,李琳.喉神经的解剖观察[J].中华医学杂志,1976,56(3):177-180. Meng ZH,Li L.Anatomical observations of laryngeal nerve[J].Natl Med J China,1976,56(3):177-180.
[18] Parolini F,Morandi A,Macchini F,et al.Cervical/thoracotomic/thoracoscopic approaches for H-type congenital tracheo-esophageal fistula:a systematic review[J].Int J Pediatr Otorhinolaryngol,2014,78(7):985-989.DOI:10.1016/j.ijporl.2014.04.011.
[19] 何秋明,王哲,钟微,等.食管闭锁术后发生食管气管瘘复发患儿的程序化治疗[J].中华小儿外科杂志,2020,41(12):1078-1083.DOI:10.3760/cma.j.cn421158-20200326-00200. He QM,Wang Z,Zhong W,et al.Programmed management of recurrent tracheoesophageal fistula[J].Chin J Pediatr Surg,2020,41(12):1078-1083.DOI:10.3760/cma.j.cn421158-20200326-00200.
相似文献/References:
[1]孔赤寰 马继东 赵英敏 李 龙.球囊扩张治疗先天性食管闭锁术后食管狭窄的时机选择[J].临床小儿外科杂志,2010,9(04):0.
[2]贾炜 余家康 钟微 李瑞琼 何秋明 夏慧敏. 先天性食管闭锁12年疗效评价[J].临床小儿外科杂志,2012,11(01):20.
[3]何静波 段星星 李皓 张号绒 彭巧玉. 超声诊断先天性食管闭锁并气管食管瘘的初步探讨[J].临床小儿外科杂志,2012,11(02):109.
[4]秦臻 王俊 蔡威. 鼻空肠营养管在ⅢA型先天性食管闭锁术后营养支持中的应用[J].临床小儿外科杂志,2014,13(02):157.
[5]朱海涛 沈淳 肖现民. 食管闭锁术后食管气管瘘复发再手术的临床分析[J].临床小儿外科杂志,2014,13(05):373.
[6]孔赤寰 李龙 李颀. 小儿气管食管瘘手术治疗分析[J].临床小儿外科杂志,2014,13(05):381.
[7]樊纬,黄金狮,陈快,等.Ⅰ型食管闭锁治疗中食管内张力延长技术的应用[J].临床小儿外科杂志,2017,16(04):360.
[8]晏萍兰,黄金狮,陈快,等.B超引导下食管闭锁术后食管吻合口瘘空肠营养管置入的方法探讨[J].临床小儿外科杂志,2017,16(05):503.
[9]张宏伟,刘丰丽,曾战东..一期胃代食管术治疗新生儿长段型食管闭锁的疗效分析[J].临床小儿外科杂志,2017,16(06):588.
[10]张玉喜,莫绪明,孙剑,等.胸腔镜在Ⅲ型食管闭锁合并气管食管瘘修补术中的应用研究[J].临床小儿外科杂志,2018,17(03):170.
Zhang Yuxi,Mo Xuming,Sun Jian,et al.The applied study of thoracoscopy during thoracoscopic surgical repair of typeⅢ esophageal atresia with tracheoesophageal fistula.[J].Journal of Clinical Pediatric Surgery,2018,17(04):170.
[11]钟微 王哲 余家康 李瑞琼. 先天性食管闭锁/食管气管瘘合并食管狭窄的治疗分析[J].临床小儿外科杂志,2012,11(03):214.
[J].Journal of Clinical Pediatric Surgery,2012,11(04):214.
备注/Memo
收稿日期:2023-3-5。
基金项目:广东省科技计划项目(2014A020212022);广州市基础研究计划基础与应用基础研究项目(202102080511)
通讯作者:何秋明,Email:qiuminghe@foxmail.com