Yang Jing,Lyu Lei,Pu Qingsong,et al.Evaluations of voiding function in children with overactive bladder by home-uroflowmetry and its clinical significance[J].Journal of Clinical Pediatric Surgery,2023,22(02):124-128.[doi:10.3760/cma.j.cn101785-202211002-005]
家庭尿流计评估膀胱过度活动儿童排尿功能的临床研究
- Title:
- Evaluations of voiding function in children with overactive bladder by home-uroflowmetry and its clinical significance
- Keywords:
- Overactive Bladder; Urination; Voiding Frequency; Maximum urine Flow Rate; Child
- 摘要:
- 目的 使用家庭尿流计评估膀胱过度活动(overactive bladder,OAB)儿童排尿功能,探讨儿童家庭尿流率测定的临床意义。 方法 收集2021年5月至2021年11月于郑州大学第一附属医院尿动力门诊就诊,诊断为OAB的7~10岁患儿20例,设为OAB组,男、女各10例;收集30例同龄健康体检儿童为正常对照组,男、女各15例;所有儿童进行家庭尿流率测定,同期对五所中小学520名同龄正常学龄儿童的排尿频率(voiding frequency,VF)进行问卷调查。对24 h、白天和夜间VF,平均每次排尿量(voided volume,VV)、最大尿流率(maximum urine flow rate,Qmax)、排尿时间(voiding time,VT)和24 h尿量(24 h-VV)等参数进行分析。 结果 OAB组24 h、白天和夜间VF显著高于正常对照组,VV、Qmax、VT显著低于正常对照组,差异有统计学意义(P＜0.05)。回收有效VF调查问卷490份,24 h VF为(6.30±0.96)次,白天VF为(5.60±0.90)次,夜间VF为(0.70±0.59)次。男童、女童的24 h、白天和夜间VF比较及不同年龄VF比较,差异均无统计学意义(P＞0.05)。家庭尿流计测得OAB组VF显著高于问卷调查VF(P＜0.05),正常对照组VF比问卷调查的VF略高,但差异无统计学意义(P＞0.05)。 结论 家庭尿流测定能准确评估OAB儿童排尿功能的变化,该项检查在家庭实施能更真实记录排尿功能的变化。
- Abstract:
- Objective To evaluate the voiding function of children with bladder overactivity (OAB) by home-uroflowmetry (HUF) and explore the clinical significance of HUF in children.Methods From May 2021 to November 2021,20 OAB children (10 boys and 10 girls) aged 7-10 years at urinary dynamics clinic of First Affiliated Hospital of Zhengzhou University (OAB group),30 age-matched volunteers (control group) (15 boys and 15 girls) underwent HUF.Voiding frequency (VF) in 520 health pupils (7-10 years) from five primary and middle schools participated in a questionnaire survey.And 24 h,day and night VF,average voiding volume (VV) per time,24 h voided volume (VV),maximum flow rate (Qmax) and voiding time (VT) were recorded.Results VF at 24 h,day and night was significantly higher in OAB group than that in control group.VV,Qmax and VT were significantly lower than that in control group.The differences were statistically significant (P<0.05).A total of 490 effective VF questionnaires were collected and 24 h,day and night VF was (6.3±0.96),(5.6±0.90) and (0.7±0.59) times respectively.No significant inter-gender differences existed in 24 h,day or night VF and there were no significant differences in VF among different ages (P>0.05).VF was significantly higher in OAB group than VF in questionnaire survey (P<0.05) and VF in control group was slightly higher than VF in questionnaire survey.However,the difference was not statistically significant (P>0.05).Conclusion Home-uroflowmetry is a useful tool for accurate and objective evaluations of voiding function of OAB children.
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备注/Memo
收稿日期:2022-11-1。
基金项目:国家自然科学基金(NSFC)(U1904208); 河南省医学科技攻关计划省部共建项目(SBGJ2018059)
通讯作者:文建国,Email:wenjg@hotmail.com