Zhang Zhiyuan,Zhong Liang,Zou Xiangyu,et al.Effect of sacral neuromodulation on urodynamic parameters in preschool children with neurogenic bladder[J].Journal of Clinical Pediatric Surgery,2021,20(11):1016-1020.[doi:10.12260/lcxewkzz.2021.11.004]
骶神经调控对学龄前期神经源性膀胱患者尿动力学参数的影响
- Title:
- Effect of sacral neuromodulation on urodynamic parameters in preschool children with neurogenic bladder
- Keywords:
- Neurogenic Bladder; Sacral Nerve Modulation; Urodynamics; Child; Preschool
- 分类号:
- R726.945;R726.9
- 摘要:
- 目的 分析骶神经调控对学龄前期神经源性膀胱患者尿动力学参数的影响，探讨骶神经调控对于学龄前期神经源性膀胱患者的治疗价值。方法 以2017年1月至2021年8月在上海儿童医学中心行骶神经调控一期电极置入术的学龄前期神经源性膀胱患者为研究对象，收集患者的临床资料及术前与术后最大膀胱容量、膀胱顺应性及逼尿肌漏尿点压力。结果 共8例患者接受骶神经调控一期电极置入术，其中女7例，男1例；接受手术时年龄3~7岁，平均年龄5.44岁。一期电极置入后，患者最大膀胱容量较术前明显增加[（118.13±59.18） mL vs.（168.38±37.47） mL]，膀胱顺应性明显改善[（5.23±3.33） mL/cmH2O vs.（7.48±3.49） mL/cmH2O]。一期电极置入术前及术后逼尿肌漏尿点压力未见明显变化。结论 骶神经调控疗法可在短期内改善学龄前期神经源性膀胱患者的膀胱容量及顺应性，其长期疗效有待进一步观察。
- Abstract:
- Objective To statistically analyze the effect of sacral neuromodulation(SNM) on urodynamic parameters in preschool children with neurogenic bladder (NB), and to explore the therapeutic value of SNM in preschoolers with NB. Methods We included in the study subjects preschool children with NB undergoing lead implantation from January 2017 to August 2021. Their clinical data and urodynamic parameters were retrospectively analyzed. Results A total of 8 children underwent lead implantation, including 7 females and 1 male. The age at the time of operation was 3-7 years old, with an average age of 5.44 years. After lead implantation, the patients’ maximum bladder capacity significantly increased (118.13±59.18 vs. 168.38±37.47), and the bladder compliance significantly improved (5.23±3.33 vs. 7.48±3.49). There was no significant change in detrusor leak point pressure before and after lead implantation. Conclusion SNM can improve the bladder capacity and compliance of preschool children with neurogenic bladder in the short term. A further observation is warranted to evaluate SNM’s long-term effect.
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备注/Memo
收稿日期:2021-08-31。
基金项目:国家自然科学基金项目（编号：81871149）
通讯作者:孙杰,Email:sunjie@scmc.com.cn