[1]冯伟,赵旭峰,崔华雷.儿童急性阑尾炎病因学研究进展[J].临床小儿外科杂志,2021,20(06):592-596.[doi:10.12260/lcxewkzz.2021.06.016]
　Feng Wei,Zhao Xufeng,Cui Hualei.Advances of etiology about acute appendicitis in children[J].Journal of Clinical Pediatric Surgery,2021,20(06):592-596.[doi:10.12260/lcxewkzz.2021.06.016]
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儿童急性阑尾炎病因学研究进展

《临床小儿外科杂志》[ISSN:1671-6353/CN:43-1380/R] 卷: 第20卷 期数: 2021年06期 页码: 592-596 栏目: 综述 出版日期: 2021-06-15
Title:
Advances of etiology about acute appendicitis in children
作者:
冯伟1;  赵旭峰1;  崔华雷2
1. 天津医科大学研究生院(天津市, 300070);
2. 天津市儿童医院(天津市, 300134)
Author(s):
Feng Wei1;  Zhao Xufeng1;  Cui Hualei2
1. Graduate School, Tianjin Medical University, Tianjin 300070, China;
2. Department of Mini-invasive Surgery, Tianjin Children’s Hospital, Tianjin 300134, China
关键词:
阑尾炎/病因学; 阑尾炎/外科学; 儿童
Keywords:
Appendicitis/ET; Appendicitis/SU; Child
分类号:
R574.61;R656.8
DOI:
10.12260/lcxewkzz.2021.06.016
摘要:
儿童急性阑尾炎是小儿外科常见的急腹症，临床上多认为其发病原因是阑尾管腔梗阻后细菌过度生长并引发炎症反应，导致阑尾肌壁、周围组织水肿和中性粒细胞浸润。但目前研究发现儿童急性阑尾炎还与原发性感染、遗传及基因易感性、饮食、环境、腹部外伤及阑尾发育畸形等因素相关。了解其病因机制有利于制定适宜的治疗方案，阑尾管腔梗阻、外伤、阑尾畸形等原因所致阑尾炎建议早期行手术治疗；而其他原因所致的儿童急性阑尾炎大多数情况下可首选抗生素治疗。本文就近年来儿童急性阑尾炎病因学的研究进展作一综述，以期提高小儿外科医生对该病的认识。
Abstract:
Acute appendicitis is a common acute abdomen in pediatric surgery.It is traditionally believed that the pathogenesis is an overgrowth of bacteria and inflammatory reactions caused by an obstruction of appendiceal cavity,resulting in edema and neutrophil infiltration in cavity,muscle wall and surrounding tissues of appendix.However,current studies have revealed that acute appendicitis in children is associated with primary infection,genetic susceptibility,diet,environment,abdominal trauma and appendiceal deformity.Understanding its etiological mechanism is conducive for selecting appropriate treatments.Early surgery is indicated for appendiceal obstruction,appendiceal deformity and trauma.Most other causes may be treated with antibiotics.This review summarized recent advances in the etiological mechanism of acute appendicitis in children for enhancing its relevant knowledge.

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备注/Memo

收稿日期:2019-03-27;。
基金项目:天津市科技计划项目（编号：14RCGFSY00150）
通讯作者:崔华雷,Email:chlfjp@sina.com

更新日期/Last Update: 1900-01-01