Sun Chao,Liu Wanlin,Wei Yishan,et al.A comparative study of potential operative risk factors for pediatric subtrochanteric fractures with titanium elastic intramedullary nail and hip locking compression plate[J].Journal of Clinical Pediatric Surgery,2020,19(07):565-572.[doi:10.3969/j.issn.1671-6353.2020.07.002]
应用弹性髓内针与髋部锁定加压钢板治疗儿童股骨转子下骨折的手术潜在风险因素对比研究
- Title:
- A comparative study of potential operative risk factors for pediatric subtrochanteric fractures with titanium elastic intramedullary nail and hip locking compression plate
- 分类号:
- R726.8;R683.42;R687.3+3
- 摘要:
- 目的 分析采用弹性髓内针与髋部锁定加压钢板行儿童股骨转子下骨折手术过程中的潜在风险因素,并对比两种方法的临床疗效。方法 回顾性分析56例儿童股骨转子下骨折患儿临床资料。患儿年龄5~10岁,依据治疗方式的不同分成:闭合复位弹性髓内钉固定联合髋人字石膏外固定治疗组(A组,34例)和切开复位髋部锁定加压钢板固定联合髋人字石膏外固定治疗组(B组,22例)。对比两组患儿的年龄、体重、性别、民族、侧别、受伤至手术的时间、术中出血量、切口长度、术中透射次数、术中耗时、住院时间、内固定取出时间及术后并发症等资料;对术后股骨颈干角和前倾角进行影像学评估,按Sanders评分原则实施双侧髋关节功能评定。结果 56例骨折全部愈合良好,两组均未发生即刻术后并发症。A组平均随访25.3个月(15~48个月),B组平均随访28.6个月(13~40个月)。A组术中出血量、输血率、切口长度(A组为双侧切口长度之和)、术中耗时(不包括麻醉、复苏及髋人字石膏固定所耗时间)、内置物取出时间的值均小于B组,差异有统计学意义(P<0.05);而术中透射次数A组为(45.74±3.22)次,显著高于B组[(15.52±0.54)次],差异具有统计学意义(P<0.05)。两组术后切口感染、内置物末端激惹率、双下肢长度比较差异均无统计学意义(P>0.05)。末次随访时根据影像学评估,双侧股骨颈干角分别为:A组(132.43±9.52)°,B组(128.44±13.51)°;前倾角分别为:A组(21.45±5.53)°,B组(24.63±6.34)°。两组患侧髋关节颈干角及前倾角与健侧相比,差异均无统计学意义(P>0.05)。根据Sanders评分标准评价患侧髋关节功能:A组中优29例、良4例、中1例,优良率97.06%;B组中优18例、良3例、中1例,优良率95.45%;差异无统计学意义(P=0.92)。结论 弹性髓内针与髋部锁定加压钢板是治疗5~10岁儿童股骨转子下骨折安全有效的方法。两种治疗方法的远期随访结果没有差异,但是使用弹性髓内针技术在缩短手术时间、减少术中出血、降低输血率以及微创切口等方面优势明显。
- Abstract:
- Objective To explore the potential operative risk factors of titanium elastic intramedullary nail versus hip locking compression plate for pediatric subtrochanteric fractures and compare the clinical efficacies of two approaches.Methods Clinical data were retrospectively analyzed for 56 children with subtrochanteric femoral fractures.The age range was 5-10 years.They were divided into closed reduction and titanium elastic intramedullary nail internal fixation plus hip spica cast fixation treatment group (A,n=34) and open reduction and hip locking compression plate internal fixation plus hip spica cast fixation group (B,n=22).Age,weight,gender,ethnicity,sideness,time from injury to operation,intraoperative blood loss,incision length,intraoperative transmission frequency,operative duration,hospitalization stay,internal fixation removal time and postoperative complications were recorded and analyzed.And imaging measurements of postoperative femoral neck shaft angle and anteversion angle and bilateral hip joint function were evaluated according to the Sanders scoring criteria.Results All 56 fractures healed well.No immediate postoperative complication occurred in neither group.The average follow-up time was 25.3(15-48) months in group A and 28.6(13-40) months in group B.The values of intraoperative blood loss,blood transfusion rate,incision length (group A was the sum of bilateral incision lengths),operative duration (excluding anesthesia,resuscitation & hip spica cast fixation time),removal time for internal fixation in group A were smaller than group B.And the differences were statistically significant (P<0.05).The intraoperative transmission frequency was significantly higher in group A than that in group B[(45.74±3.22) vs (15.52±0.54)].And the difference was statistically significant (P<0.05).No statistically significant inter-group difference existed in postoperative incision infection,irritability of implant end or length of lower extremities (P>0.05).At the last follow-up,based upon radiographic measurements,bilateral femoral neck shaft angles were as follows:group A (132.43±9.52)°,group B (128.44±13.51)°;anteversion angles:group A (21.45±5.53)°,group B (24.63±6.34)°.As compared with healthy side,neck shaft angle and anteversion angle of hip joint had no statistically significant differences (P>0.05).According to the Sanders scoring criteria,hip function was excellent (n=29),decent (n=4) and moderate (n=1) in group A with an excellent-decent rate of 97.06%;excellent (n=18),decent (n=3) and moderate (n=1) in group B with an excellent-decent rate of 95.45%;The inter-group difference was not statistically significant (P=0.92).Conclusion Titanium elastic intramedullary nail and hip locking compression plate is both safe and effective for pediatric subtrochanteric femoral fractures in children aged 5-10 years.No inter-group difference exists in long-term follow-up outcomes.However,use of titanium elastic intramedullary nail technology offers obvious advantages in terms of shorter operative duration,lesser intraoperative bleeding,lower blood transfusion rate and mini-invasive incisions.
参考文献/References:
1 Jarvis J,Davidson D,Letts M.Management of subtrochanteric fractures in skeletally immature adolescents[J].J Trauma,2006,60(3):613-619.DOI:10.1097/01.ta.0000197606.63124.9e.
2 Pombo MW,Shilt JS.The definition and treatment of pediatric subtrochanteric femur fractures with titanium elastic nails [J].J Pediatr Orthop,2006,26(3):364-370.DOI:10.1097/01.bpo.0000203005.50906.41.
3 Xu Y,Bian J,Shen K,et al.Titanium elastic nailing versus locking compression plating in school-aged pediatric subtrochanteric femur fractures[J].Medicine (Baltimore),2018,97(29):e11568-e11574.DOI:10.1097/MD.0000000000011568.
4 Li Y,Heyworth BE,Glotzbecker M,et al.Comparison of titanium elastic nail and plate fixation of pediatric subtrochanteric femur fractures[J].J Pediatr Orthop,2013,33(3):232-238.DOI:10.1097/BPO.0b013e318288b496.
5 Porter SE,Booker GR,Parsell DE,et al.Biomechanical analysis comparing titanium elastic nails with locked plating in two simulated pediatric femur fracture models[J].J Pediatr Orthop,2012,32(6):587-593.DOI:10.1097/BPO.0b013e31824b7500.
6 Fein LH,Pankovich AM,Spero CM,et al.Closed flexible intramedullary nailing of adolescent femoral shaft fractures[J].J Orthop Trauma,1989,3(2):133-141.DOI:10.1097/00005131-198906000-00008.
7 Mazda K,Khairouni A,Pennecot GF,et al.Closed flexible intramedullary nailing of the femoral shaft fractures in children[J].J Pediatr Orthop B,1997,6(3):198-202.DOI:10.1097/01202412-199707000-00008.
8 Sanders R,Regazzoni P.Treatment of subtrochanteric femur fractures using the dynamic condylar screw[J].J Orthop Trauma,1989,3(3):206-213.DOI:10.1097/00005131-198909000-00005.
9 Flynn JM,Hresko T,Reynolds RAK,et al.Titanium elastic nails for pediatric femur fractures:a multicenter study of early results with analysis of complications[J].J Pediatr Orthop,2001,21(1):4-8.DOI:10.1097/00004694-200101000-00003.
10 Ireland DCR,Fisher RL.Subtrochanteric fractures of the femur in children[J].Clin Orthop Relat Res,1975,110:157-166.DOI:10.1097/00003086-197507000-00020.
11 Sink EL,Gralla J,Repine M.Complications of pediatric femur fractures treated with titanium elastic nails:a comparison of fracture types[J].J Pediatr Orthop,2005,25(5):577-580.DOI:10.1097/01.bpo.0000164872.44195.4f.
12 Sink EL,Faro F,Polousky J,et al.Decreased complications of pediatric femur fractures with a change in management[J].J Pediatr Orthop,2010,30(7):633-637.DOI:10.1097/BPO.0b013e3181efb89d.
13 Sela Y,Hershkovich O,Nir SL,et al.Pediatric femoral shaft fractures:treatment strategies according to age-13 years of experience in one medical center[J].J Orthop Surg Res,2013,8(1):23-28.DOI:10.1186/1749-799X-8-23.
14 Jarvis J,Davidson D,Letts M.Management of subtrochanteric fractures in skeletally immature adolescents[J].J Trauma,2006,60(3):613-619.DOI:10.1097/01.ta.0000197606.63124.9e.
15 Nascimento FPD,Santili C,Akkari M,et al.Flexible intramedullary nails with traction versus plaster cast for treating femoral shaft fractures in children:comparative retrospective study[J].Sao Paulo Med J,2013,131(1):5-12.DOI:10.1590/s1516-31802013000100002.
16 Hedequist D,Bishop J,Hresko T.Locking plate fixation for pediatric femur fractures[J].J Pediatr Orthop,2008,28(1):6-9.DOI:10.1097/bpo.0b013e31815ff301.
17 Saseendar S,Menon J,Patro DK,et al.Treatment of femoral fractures in children:is titanium elastic nailing an improvement over hip spica casting?[J].J Child Orthop,2010,4(3):245-251.DOI:10.1007/s11832-010-0252-z.
18 Wilkins KE.Principles of fracture remodeling in children[J].Injury,2005,36:S-A3-S-A11.DOI:10.1016/j.injury.2004.12.007.
19 陈博昌,王志刚,杨杰,等.弹性髓内针交叉固定治疗儿童长骨骨折[J].中国矫形外科杂志,2003,11(9):598-601.DOI:CNKI:SUN:ZJXS.0.2003-09-008. Chen BC,Wang ZG,Yang J,et al.Efficacy of flexible intramedullary nailing for long bone fractures in children[J].J Orthop China,2003,11(9):598-601.DOI:CNKI:SUN:ZJXS.0.2003-09-008.
20 Mazda K,Khairouni A,Pennecot GF,et al.Closed flexible intramedullary nailing of the femoral shaft fractures in children[J].J Pediatr Orthop B,1997,6(3):198-202.DOI:10.1097/01202412-199707000-00008.
21 Jauquier N,Doerfler M,Haecker FM,et al.Immediate hip spica is as effective as,but more efficient than,flexible intramedullary nailing for femoral shaft fractures in pre-school children[J].J Child Orthop,2010,4(5):461-465.DOI:10.1007/s11832-010-0279-1.
22 Parikh SN,Nathan ST,Priola MJ,et al.Elastic nailing for pediatric subtrochanteric and supracondylar femur fractures[J].Clin Orthop Relat Res,2014,472(9):2735-2744.DOI:10.1007/s11999-013-3240-z.
23 Ellis HB,Ho CA,Podeszwa DA,et al.A comparison of locked versus nonlocked Enders rods for length unstable pediatric femoral shaft fractures[J].J Pediatr Orthop,2011,31(8):825-833.DOI:10.1097/BPO.0b013e31822ed34d.
24 Hedequist D,Bishop J,Hresko T.Locking plate fixation for pediatric femur fractures[J].J Pediatr Orthop,2008,28(1):6-9.DOI:10.1097/bpo.0b013e31815ff301.
25 Moroz LA,Launay F,Kocher MS,et al.Titanium elastic nailing of fractures of the femur in children.Predictors of complications and poor outcome[J].J Bone Joint Surg Br,2006,88(10):1361-1366.DOI:10.1302/0301-620X.88B10.17517.
26 Polderman KH.Mechanisms of action,physiological effects,and complications of hypothermia[J].Crit Care Med,2009,37(7 Suppl):S186-S202.DOI:10.1097/CCM.0b013e3181aa5241.
27 Mervis JS,Phillips TJ.Pressure ulcers:prevention and management[J].J Am Acad Dermatol,2019,81(4):893-902.DOI:10.1016/j.jaad.2018.12.068.
28 Robert-Ebadi H,Righini M.Management of distal deep vein thrombosis[J].Thromb Res,2017,149:48-55.DOI:10.1016/j.thromres.2016.11.009.
29 De Baerdemaeker L,Margarson M.Best anaesthetic drug strategy for morbidly obese patients[J].Curr Opin Anaesthesiol,2016,29(1):119-128.DOI:10.1097/ACO.0000000000000286.
30 John MF,Richard MS.Management of pediatric femoral shaft fractures[J].J Am Acad Orthop Surg,2004,12(5):347-359.DOI:10.1016/j.jse.2004.03.003.
31 黄立明,汪文涛,潘源城,等.带锁髓内钉和锁定钢板治疗青少年股骨干骨折的对比研究[J].临床小儿外科杂志,2019,18(2):124-129.DOI:10.3969/j.issn.1671-6353.2019.02.011. Huang LM,Wang WT,Pan YC,et al.Comparison of interlocking intramedullary nail versus locking plate fixation for juvenile femoral shaft fractures[J].J Clin Ped Sur,2019,18(2):124-129.DOI:10.3969/j.issn.1671-6353.2019.02.011.
32 Osterman JL,Arora S.Blood product transfusions and reactions[J].Hematol Oncol Clin N Am,2017,31(6):1159-1170.DOI:10.1016/j.hoc.2017.08.014.
33 Lavoie J.Blood transfusion risks and alternative strategies in pediatric patients [J].Paediatr Anaesth,2011,21(1):14-24.DOI:10.1111/j.1460-9592.2010.03470.x.
34 Giuseppe M,Ugo F,Emanuela F,et al.Increased cancer risk among surgeons in an orthopaedic hospital[J].Occup Med (Lond),2005,55(6):498-500.DOI:10.1093/occmed/kqi048.
35 Little MP,Kitahara CM,Cahoon EK,et al.Occupational radiation exposure and risk of cataract incidence in a cohort of US radiologic technologists[J].Eur J Epidemiol,2018,33(12):1179-1191.DOI:10.1007/s10654-018-0435-3.
36 Bhatti P,Struewing JP,Alexander BH,et al.Polymorphisms in DNA repair genes,ionizing radiation exposure and risk of breast cancer in U.S.Radiologic technologists[J].Int J Cancer,2008,122(1):177-182.DOI:10.1002/ijc.23066.
37 Kelly BA,Naqvi M,Rademacher ES,et al.Fracture table application for pediatric femur fractures:incidence and risk factors associated with adverse outcomes[J].J Pediatr Orthop,2017,37(6):e353-e356.DOI:10.1097/BPO.0000000000001036.
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备注/Memo
收稿日期:2019-05-27。
基金项目:国家临床重点专科建设费用资助项目(编号:财社[2010]305号)
通讯作者:韦宜山,Email:3276844912@qq.com