Zhong Jiafei,Gu Shuo.Recent advances in perinatal management of neural tube defects[J].Journal of Clinical Pediatric Surgery,2020,19(06):548-553.[doi:10.3969/j.issn.1671-6353.2020.06.017]
神经管畸形围生期处理新进展
- Title:
- Recent advances in perinatal management of neural tube defects
- Keywords:
- Neural Tube Defects; Perinatal Period
- 分类号:
- R739.4
- 摘要:
- 随着影像学等技术的进步，神经管畸形围生期处理方法在过去的30年经历了飞跃式发展。过去，神经管畸形在出生时才能被发现或者因表现不明显而被漏诊，病死率高且预后极差；现在，产前诊断及针对性处理手段的进步使得围生期处理神经管畸形理念进一步更新，包括主动预防、加强孕期产检及咨询、分娩方式及时机的选择、针对性处理计划等，极大地提高了神经管畸形患儿生存率及生活质量。本文通过查阅、分析、总结最新文献，对神经管畸形围生期处理最新进展作一综述。
- Abstract:
- With a rapid progress of imaging and other techniques,perinatal management of neural tube defects (NTDs) has undergone a quantum leap over the last three decades.Previously NTDs were only discovered at birth or underdiagnosed so that there were a high mortality and a poor prognosis.Current advances in prenatal diagnosis and targeted management have led to a renewal of perinatal management including active preventions,intensive prenatal examinations and consultations,selections of delivery mode and timing and targeted treatment plans,etc.,greatly improved patient survival rate and quality-of-life.This review has summarized the latest literature reports.Perinatal managements and recent advances of NTDs are thoroughly reviewed.
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备注/Memo
收稿日期:2020-02-10。
基金项目:国家重点研发计划（编号：2018YFC1002400）；国家重点研发计划（编号：2018YFC1002401）
通讯作者:顾硕,Email:gushuo007@163.com