Guo Qiang,Zhang Wei,Zhu Dan.Surgical strategies and scope of resecting epileptic low-grade tumors in children[J].Journal of Clinical Pediatric Surgery,2019,18(09):719-722.[doi:10.3969/j.issn.1671-6353.2019.09.002]
儿童致痫性低级别肿瘤的手术策略与切除范围设计
- Title:
- Surgical strategies and scope of resecting epileptic low-grade tumors in children
- Keywords:
- Epilepsy; Neoplasms; Surgical Procedures; Operative; Games; Experimental; Child
- 分类号:
- R726.1;R739.4;R742.1
- 摘要:
- 儿童低级别肿瘤往往合并顽固性癫痫，严重影响患儿生活质量。外科治疗的目的应兼顾肿瘤治疗、发作控制与神经功能保护三个方面。在肿瘤全切除的基础上进一步切除致痫灶，往往能更好地控制发作。在手术切除范围的设计上，应综合考虑肿瘤部位（颞叶或颞叶以外、功能或非功能区等）、肿瘤性质、癫痫术前评估结果、患儿自身功能状态及家庭收入水平等因素。
- Abstract:
- Low-grade tumors (LGT) are often associated with refractory epilepsy in pediatric patients,which seriously affect their quality of life. Aims of surgical treatments for LGT should include treatments of the tumors, seizures controlling and preservation of neural function.Usually,extended resection of epileptogenic zone following the tumor total removal can yield a better outcome in seizure control than pure lesionectomy.For designing the extension of surgical resection,some key factors should be considered,such as the location of the tumors (temporal or extra-temporal,functional or non-functional),the possible pathology of the tumor,results of the pre-surgical evaluation for epilepsy,the status of neural function of the patients,as well as family incomes.
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备注/Memo
收稿日期:2019-04-28。
基金项目:广东省医学科学技术研究基金项目（编号：B2018169）