Chen Gong,Zheng Shan.Etiology,diagnosis and treatment of pediatric esophageal strictures[J].Journal of Clinical Pediatric Surgery,2019,18(06):437-441.[doi:10.3969/j.issn.1671-6353.2019.06.001]
儿童食管狭窄的病因及诊治进展
- Title:
- Etiology,diagnosis and treatment of pediatric esophageal strictures
- 分类号:
- R726.1;R571+.1
- 摘要:
- 食管狭窄相关疾病包括：先天性食管狭窄、食管闭锁术后狭窄、胃食管反流伴发狭窄、食管化学烧灼伤引发狭窄、嗜酸性食管炎、放化疗后食管狭窄等。目前我国难治性食管狭窄多为食管化学烧灼伤后狭窄。食管连续扩张是治疗此类疾病的首选方法，疗效不佳时可配合使用激素、丝裂霉素等药物。食管替代术是该类疾病的最后防线。食管狭窄相关疾病诊治水平还需要多中心联合才能不断提高。
- Abstract:
- Esophageal stricture-related diseases include congenital esophageal stricture,stenosis after esophageal anastomosis,gastroesophageal reflux,corrosive esophageal injuries,eosinophilic esophagitis and esophageal stricture after radiotherapy.At present,most refractory strictures in China are caused by corrosive esophageal injuries.Continuous dilatation is an effective treatment.When curative effect is poor,it may be combined with steroid and mitomycin.Esophageal replacement is the last resort.For improving the diagnostic and therapeutic levels of esophageal stenosis-related diseases,multi-center researches are required.
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备注/Memo
收稿日期:2019-05-23。
基金项目:国家自然科学基金（编号：81873545；81700450）
通讯作者:郑珊,Email:szheng@shmu.edu.cn