[1]刘娜,张川,杨磊,等. 医用粘合胶及硅胶敷料对小儿先心病术后胸部正中切口瘢痕增生的抑制效果分析[J].临床小儿外科杂志,2019,18(01):45-48.
　Liu Na,Zhang Chuan,Yang Lei,et al. Clinical analysis of scar hyperplasia after chest median incision in children with congenital heart disease.[J].Journal of Clinical Pediatric Surgery,2019,18(01):45-48.
点击复制

 医用粘合胶及硅胶敷料对小儿先心病术后胸部正中切口瘢痕增生的抑制效果分析

《临床小儿外科杂志》[ISSN:1671-6353/CN:43-1380/R] 卷: 第18卷 期数: 2019年01期 页码: 45-48 栏目: 论著 出版日期: 2019-01-20
Title:
 Clinical analysis of scar hyperplasia after chest median incision in children with congenital heart disease.
作者:
 刘娜; 张川; 杨磊; 等
 河北医科大学第三医院整形外科
Author(s):
 Liu Na; Zhang Chuan; Yang Lei; Liu Lei; Xie Meng.
 Department of Plastic Surgery，Shijiazhuang 050051,China.
关键词:
 ; 瘢痕增生;  医用粘合胶;  心脏病/先天性;  手术后期间;  儿童
Keywords:
 ; Scar Hyperplasia;  Medical Glue;  Heart Diseases/CN; Postoperative Period; Child
文献标志码:
A
摘要:
 目的探讨医用粘合胶及硅胶敷料抑制小儿先心病术后胸部正中切口瘢痕增生的效果。方法选取河北医科大学第三医院接受胸部正中切口先心病矫治术的患儿160例，遵循随机化原则分为4组，其中A组为医用粘合胶治疗组，B组为硅胶敷料治疗组，C组为医用粘合胶序贯硅胶敷料治疗组，D组为对照组，每组各40例。分别于治疗后1、3、6、12个月观察伤口瘢痕形成情况，采用温哥华瘢痕评定量表对瘢痕色泽、血管分布、厚度、柔软度情况进行评分，并进行统计学分析。结果从不同时间段的治疗结果来看，A、B、C、D组瘢痕增生评分均随观察时间的延长而增加，其中A、B、D组各时间段两两间瘢痕评分差异均有统计学意义（P<0.05），而C组治疗后第6、12个月与治疗前相比差异有统计学意义（P<0.05）；从不同组别来看，治疗后第1个月，4组患儿瘢痕增生评分差异无统计学意义（P>0.05）；治疗后第3、6、12个月，A、B和C组患儿瘢痕增生评分均显著低于D组（P<0.05）；治疗后第3、6、12个月，C组患儿瘢痕增生评分显著低于A和B组（P<0.05）；但A、B两组间差异无统计学意义（P>0.05）；治疗过程中患儿均未出现显著不良反应。结论采用医用粘合胶序贯硅胶敷料可有效抑制小儿先心病手术后胸部正中切口的瘢痕增生。
Abstract:
 ObjectiveTo explore the efficacy of using medical adhesive and silicagel dressing for scar hyperplasia after chest median incision in children with congenital heart disease (CHD).MethodsA total of 160 CHD cases underwent median sternotomy.They were randomly divided into 4 groups of A (medical adhesive treatment),B (silicone dressing treatment),C (sequential medical adhesive silicone dressing treatment) and D (control) (n=40 each).Formation of wound scar was evaluated after treatment for 1,6,3,12 months.The Vancouver Scar Scale was used for assessing scar color,vascular distribution,thickness and softness.Then statistical analysis was performed.ResultsThe hypertrophic scar scores of A,B and C groups were lower than those of D group after 1 month.However the difference was not statistically significant (P>0.05);after 3,6 and 12 months,the hypertrophic scar scores of A,B and C groups were lower than those of D group.And the differences were statistically significant (P<0.05);the hypertrophic scar score of C group was lower than A and B groups.The difference was statistically significant (P<0.05).However,no significant differences existed between A and B groups.None of them had no obvious adverse reactions during treatment.ConclusionMedical adhesive sequential silicone dressing can significantly suppress the proliferation of scar tissue after middle thoracic incision in children with congenital heart disease.

相似文献/References:

[1]刘婷婷 张钦明 周红 焦丽丽 陈永卫. 肠内营养在儿童胰腺外伤治疗中的应用[J].临床小儿外科杂志,2011,10(02):84.
　LIU Ting ting,ZHANG Qin ming,ZHOU Hong,et al. Enteral nutrition treatment in the application of pancreas trauma of children.[J].Journal of Clinical Pediatric Surgery,2011,10(01):84.
[2]吴卫卫 汪健 黄顺根. 肠外营养导致大鼠肝细胞炎症因子及受体基因表达的变化及临床意义[J].临床小儿外科杂志,2011,10(02):87.
　 Parenteral Nutrition Leads to Alteration of Inflammation Cytokines and Receptors Gene Expression in the Rat[J].Journal of Clinical Pediatric Surgery,2011,10(01):87.
[3]于增文 杨杨 李索林 耿娜 李英超 李萌 马亚贞. 腹腔镜下十二指肠单层缝合吻合术的实验研究与临床应用[J].临床小儿外科杂志,2011,10(02):90.
　YU Zen gwen,YANG Yang,LI Suo lin,et al. The experimental studies and clinical applications of laparoscopic duodenal singlelayer sutured anastomosis in children.[J].Journal of Clinical Pediatric Surgery,2011,10(01):90.
[4]徐织 王剑 傅启华 杨波 宋云海 鲍南.中国人群神经管缺陷VANGL1基因突变的筛查及关联研究[J].临床小儿外科杂志,2011,10(02):94.
　 Mutation screening and associated study of VANGL1 gene in chinese patients with Neural Tube Defects.[J].Journal of Clinical Pediatric Surgery,2011,10(01):94.
[5]丁晋阳 莫绪明 顾海涛 孙剑 彭卫 戚继荣 沈立 束亚琴 钱龙宝. 延迟关胸技术在婴儿复杂危重先心病手术中的应用[J].临床小儿外科杂志,2011,10(02):98.
　DING Jin yang,MO Xu ming,GU Hai tao,et al. Delayed Sternal Closure following operations for complex and severe congenital heart disease in infant[J].Journal of Clinical Pediatric Surgery,2011,10(01):98.
[6]吴臻斐 林孝坤 秦乐 林进汉 李仲荣 陈肖鸣. 西地那非对大鼠单侧睾丸扭转后对侧睾丸的影响及作用研究[J].临床小儿外科杂志,2011,10(02):101.
　[J].Journal of Clinical Pediatric Surgery,2011,10(01):101.
[7]王贤书 张晓茹 杨志国 程征海 岳芳 曹红宾 李德泽. 脑室腹腔分流术治疗婴儿脑积水120例 [J].临床小儿外科杂志,2011,10(02):105.
[8]杨洋 张潍平 彭芸 温洋 杨吉刚.两种输尿管不全梗阻肾积水动物模型制作方法的比较[J].临床小儿外科杂志,2011,10(02):107.
　 Comparison of two different methods to establish animal model of hydronephrosis due to incomplete ureteral obstruction.[J].Journal of Clinical Pediatric Surgery,2011,10(01):107.
[9]俞钢 朱小春 葛午平 林炎坤 金龙 劳伟华 史浩 肖尚杰 洪淳 周佳亮 傅晓静. 胎儿外科相关疾病的产前诊断及干预[J].临床小儿外科杂志,2011,10(02):111.
　 The antenatal diagnosis, tassessment, and therapy of fetal surgical anomalies[J].Journal of Clinical Pediatric Surgery,2011,10(01):111.
[10]刘国庆 王剑锋 朵永福 李杰荣 陈一平 黄振强 叶章群. 妊娠期尿结石对胎儿早产流产的影响[J].临床小儿外科杂志,2011,10(02):115.
　 Urolithiasis influence to develop of fetus in gestation period[J].Journal of Clinical Pediatric Surgery,2011,10(01):115.

更新日期/Last Update: 2019-01-22