临床小儿外科杂志

目的分析血管瘤并血小板减少综合征经介入栓塞治疗的效果。方法收集2011年12月至2015年12月间本院收治的7例KM综合征患儿作为研究对象,所用病例在DSA透视下进行选择性动脉栓塞治疗。结果 7例患者中,颌面部1例,躯干3例,肩部2例,颈部1例。血小板均在60×109/L以下,最少7×109/L。治愈4例,好转3例,无死亡病例,介入治疗效果良好。结论血管瘤并血小板减少综合征患儿如果能早期选择介入治疗,多数病例预后较好,但无法根除原发灶的广泛性血管畸形。介入手术治疗对颌面部、颈部、躯干部位的KM综合征疗效确切,副反应小,值得推广。

Objective To evaluate the clinical outcomes of Kasabach-Merrit syndrome and examine its interventional treatments. Methods This retrospective study was conducted for 7 patients with Kasabach-Merrit syndrome receiving selective arterial embolization by DSA(digital subtraction angiography). Results The sites included maxillofacial region(n=1),trunk(n=3),shoulder(n=2)and neck(n=1).The count of platelet7×109/L to 60×109/L.The outcomes were cure(n=4)and improvement(n=3). Conclusion At an early stage,this disease may be treated interventionally with an excellent prognosis.However,generalized primary vascular malformations are not eradicated in most cases.The prognosis is poor for combined platelet reduction.Interventional surgery of jaw-face,neck and trunk area of KM syndrome is effective and have few side effects.It is worthy of wider promotion.

引言
1 材料与方法
2 结果
3 讨论

表1 7例KM综合征患儿临床资料<br/>Table 1 Clinical data of 7 patients with KM syndrome

表1 7例KM综合征患儿临床资料
Table 1 Clinical data of 7 patients with KM syndrome

图1 第7例KM综合征患儿左侧腮腺区血管瘤介入栓塞术前MRI图片; 图2第7例KM综合征患儿左侧腮腺区血管瘤介入栓塞术后3个月MRI图片<br/>Fig.1 Pre-operative MRI images of Case No.7 of KM syndrome(left parotid hemangioma) Fig.2 Case No.7 of KM syndrome(left parotid hemangioma)was followed by 3 months follow-up MRI images at Month 3(left parotid area hemangioma smaller than before and platelet recovered to 216×109/L)

图1 第7例KM综合征患儿左侧腮腺区血管瘤介入栓塞术前MRI图片; 图2第7例KM综合征患儿左侧腮腺区血管瘤介入栓塞术后3个月MRI图片
Fig.1 Pre-operative MRI images of Case No.7 of KM syndrome(left parotid hemangioma) Fig.2 Case No.7 of KM syndrome(left parotid hemangioma)was followed by 3 months follow-up MRI images at Month 3(left parotid area hemangioma smaller than before and platelet recovered to 216×109/L)

图3 第7例KM综合征患儿左侧腮腺区血管瘤介入栓塞术中采集的DSA图片。a,术前左侧颈动脉造影动脉期。b,动脉造影瘤体染色期。c,微导管动脉造影瘤体染色期。d,栓塞术后颈动脉造影瘤体染色期,肿瘤染色区大部分消失。<br/>Fig.3 For case No.7 of KM syndrome(left parotid hemangioma),DSA images were collected during embolization. a,Preoperative angiography of left carotid artery; b,Arterial tumor staining period using catheter; c,Arterial tumor staining using microtubule; d,During the period of the postoperative,most staining areas disappeared on carotid angiography.

图3 第7例KM综合征患儿左侧腮腺区血管瘤介入栓塞术中采集的DSA图片。a,术前左侧颈动脉造影动脉期。b,动脉造影瘤体染色期。c,微导管动脉造影瘤体染色期。d,栓塞术后颈动脉造影瘤体染色期,肿瘤染色区大部分消失。
Fig.3 For case No.7 of KM syndrome(left parotid hemangioma),DSA images were collected during embolization. a,Preoperative angiography of left carotid artery; b,Arterial tumor staining period using catheter; c,Arterial tumor staining using microtubule; d,During the period of the postoperative,most staining areas disappeared on carotid angiography.

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备注

引言

1 材料与方法

2 结果

3 讨论

期刊信息

备注

引言

1 材料与方法

2 结 果

3 讨 论

期刊信息

2 结果

3 讨论