[1]曲志博,张浩然.自噬调控在神经母细胞瘤中的作用研究进展[J].临床小儿外科杂志,2019,18(03):242-246,249.[doi:10.3969/j.issn.1671-6353.2019.03.017]
 Qu Zhibo,Zhang Haoran.Advances in autophagy regulation and neuroblastoma[J].Journal of Clinical Pediatric Surgery,2019,18(03):242-246,249.[doi:10.3969/j.issn.1671-6353.2019.03.017]
点击复制

自噬调控在神经母细胞瘤中的作用研究进展

参考文献/References:

1 Deter RL, Baudhuin P, De Duve C.Participation of lysosomes in cellular autophagy induced in rat liver by glucagon[J].J Cell Biol, 1967, 35(2):C11-C16.DOI:10.1083/jcb.35.2.C11.
2 Levine B, Kroemer G.Autophagy in the pathogenesis of disease[J].Cell, 2008, 132(1):27-42.DOI:10.1016/j.cell.2007.12.018.
3 Castel V, Grau E, Noguera R, et al.Molecular biology of neuroblastoma[J].Clin Transl Oncol, 2007, 9(8):478-483.DOI:10.1007/s12094-007-0091-7.
4 Kiyonari S, Kadomatsu K.Neuroblastoma models for insights into tumorigenesis and new therapies[J].Expert Opin Drug Discov.2015, 10(1):53-62.DOI:10.1517/17460441.2015.974544.
5 Chen S, Zhou C, Ma X, Gong L.Abnormality of anapastic lymphoma kinase gene and its expression in pediatric neuroblastoma[J].Chinese Journal of Pathology, 2014, 43(8):541-545.DOI:10.3760/cma.j.issn.0529-5807.2014.08.009.
6 Shintani T, Klionsky DJ.Autophagy in health and disease:A double-edged sword[J].Science, 2004, 306(5698):990-995.DOI:10.1126/science.1099993.
7 Liu J, Fan L, Wang H, et al.Autophagy, a double-edged sword in anti-angiogenesis therapy[J].Med Oncol, 2016, 33(1):10.DOI:10.1007/s12032-015-0721-9.
8 Mizushima N, Levine B, Cuervo AM, et al.Autophagy fights disease through cellular self-digestion[J].Nature, 2008, 451(7182):1069-1075.DOI:10.1038/nature06639.
9 Yuan H, Li AJ, Ma SL, Cui LJ, et al.Inhibition of autophagy significantly enhances combination therapy with sorafenib and HDAC inhibitors for human hepatoma cells[J].World J Gastroenterol, 2014, 20(17):4953-4962.DOI:10.3748/wjg.v20.i17.4953.
10 Klionsky DJ.The molecular machinery of autophagy:unanswered questions[J].J Cell Sci, 2005, 118(Pt 1):7-18.DOI:10.1242/jcs.01620.
11 Mizushima Noboru, Levine Bet, Cuervo AM.Autophagy fights disease through cellular self-digestion[J].Nature, 2008, 451(7182):1069-1075.DOI:10.1038/nature06639.
12 Chen N, Karantza V.Autophagy as a therapeutic target in cancer[J].Cancer Biol Ther, 2011, 11(2):157-168.DOI:10.4161/cbt.11.2.14622.
13 Matsuura A, Tsukada M, Wada Y, et al.Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae[J].Gene, 1997, 192(2):245-250.DOI:10.1016/s0378-1119(97)00084-x.
14 Feng YC, Yao ZY, Klionsky DJ.How to control self-digestion:transcriptional, post-transcriptional and post-translational regulation of autophagy[J].Trends Cell Biol, 2015, 25(6):354-363.DOI:10.1016/j.tcb.2015.02.002.
15 Ganley IG, Lam du H, Wang J, et al.ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy[J].J Biol Chem, 2009;284(18):12297-12305.DOI:10.1074/jbc.M900573200.
16 Kim J, Kundu M, Viollet B, et al.AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1[J].Nat Cell Biol, 2011, 13(2):132-141.DOI:10.1038/ncb2152.
17 Egan DF, Shackelford DB, Mihaylova MM, Gelino S, Kohnz RA, Mair W, Vasquez DS, Joshi A, Gwinn DM, Taylor R, Asara JM, Fitzpatrick J, Dillin A, et al.Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy[J].Science, 2011, 331(6):456-461.DOI:10.1126/science.1196371.
18 Maycotte P, Thorburn A.Autophagy and cancer therapy[J].Cancer Biol Ther, 2011, 11(2):127-137.DOI:10.4161/cbt.11.2.14627.
19 Yu J, Lan L, Lewin SJ, et al.Identification of novel small molecule Beclin 1mimeics activating autophagy[J].Oncotarget, 2017, 8(31):51355-51369.DOI:10.18632/oncotarget.17977.
20 Li Yue, Zhao Yuting, Su Minfei, et al.Structural insights into the interaction of the conserved mammalian proteins GAPR-1 and Beclin 1, a key autophagy protein[J].Acta Crystallogr D Struct Biol, 2017, 73(Pt 9):775-792.DOI:10.1107/S2059798317011822.
21 Lock R, Roy S, Kenific CM, Su JS, Salas E, Ronen SM, Debnath J.Autophagy facilitates glycolysis during Ras-mediated oncogenic teansformation[J].Mol Biol Cell, 2011, 22(2):165-178.DOI:10.1091/mbc.E10-06-0500.
22 柳慧芳, 白双, 王鹏, 等.Ras影响肿瘤的另一种机制:自噬[J].生命的化学.2016, 36(2):245-251.DOI:10.13488/j.smhx.20160218. Liu HF, Bai S, Wang P, et al.Alterative mechanism of Ras influencing tumors:autophagy[J].Life Chemistry.2016, 36(2):245-251.DOI:10.13488/j.smhx.20160218.
23 智立柱, 董芽倩, 许成学.Ha-ras癌基因蛋白在小儿神经母细胞瘤中的表达及其临床意义[J].中华小儿外科杂志, 1998, 19(1):26-29. Zhi LZ, Dong YQ, Xu CX.Expression and clinical significance of Ha-ras oncogenic protein in pediatric neuroblastomas[J].Chinese Journal of Pediatric Surgery, 1998, 19(1):26-29.DOI:10.3760/cma.j.issn.0253-3006.1998.01.010.
24 Giatromanolaki A, Sivridis E, Mendrinos S, et al.Autophagy proteins in prostate cancer:relation with anaerobic metabolism and Gleason score[J].Urol Oncol, 2014, 32(39):e11-38.DOI:10.1016/j.urolonc.2013.04.003.
25 Shintani T, Klionsky DJ.Autophagy in health and disease:A double-edged sword[J].Science, 2004, 306(5698):990-995.DOI:10.1126/science.1099993.
26 Amaravadi R, Kimmelman AC, White E.Recent insights into the function of autophagy in cancer[J].Genes De, 2016, 30(17):1913-1930.DOI:10.1101/gad.287524.116.
27 Hernández-Tiedra S, Fabriàs G, Dávila D, et al.Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization[J].Autophagy, 2016, 16(1):1-17.DOI:10.1080/15548627.2016.1213927.
28 曲志博, 刘连新, 尹大龙, 等.三氧化二砷对乳腺癌细胞凋亡及线粒体跨膜电位的影响[J].中华外科杂志, 2007, 45(13):883-884.DOI:10.3760/j.issn:0529-5815.2007.13.007 Qu ZB, Liu LX, Yan DL, et al.Effect of Trisenox upon cell apoptosis and mitochondrial transmembrane potential[J].Chinese Journal of Surgery, 2007, 45(13):883-884.DOI:10.3760/j.issn:0529-5815.2007.13.007
29 He C, Klionsky DJ.Regulation mechanisms and signaling pathways of autophagy[J]. Annual Review of Genetics, 2009, 43(1):67-93.DOI:10.1146/annurev-genet-102808-114910.
30 Samardzija G, Stevovic TK, Djuricic S, et al.Aggressive human neuroblastomas show a massive increase in the numbers of autophagic vacuoles and damaged mitochondria[J].Ultrastruct Pathol, 2016, 40(5):240-248.DOI:10.1080/01913123.2016.1187689.
31 Nevena Z, Gordana TK, Maja M, et al.Coordinated activation of AMP-activated protein knise, extracellular signal-regulated kinse, and autophagy regulates phorbol myristated acetate-induced differentiation of SH-SY5Y neuroblastoma cells[J].Journal of Neurochemistry, 2015, 133(3):223-232.DOI:10.1111/jnc.12980.
32 王忠强, 杨剑虹, 姚秀芬, 等.抑制beclin-1信号通路对缺血再灌注后神经母细胞瘤N2a细胞自噬的影响[J].中国临床神经外科杂志, 2011, 16(8):481-484.DOI:10.3969/j.issn.1009-153X.2011.08.012. Wang ZQ, Yang JH, Yao XF, et al.Effect of suppressing beclin-1 signal transduction pathway on cell autophagy of neuroblastoma N2a after ischemia-reperfusion[J].Chinese Journal of Clinical Neurosurgery, 2011, 16(8):481-484.DOI:10.3969/j.issn.1009-153X.2011.08.012.
33 王雪晶, 滕军放, 丁雪冰, 等.丙戊酸促进神经母细胞瘤细胞自噬性死亡.肿瘤基础与临床[J].2015, 28(2):93-95.DOI:10.3969/j.issn.1673-5412.2015.02.001. Wang XJ, Teng JF, Ding XB, et al.Promoting autophagy of neuroblastoma by valproic acid[J].Journal of Basic and Clinical Oncology, 2015, 28(2):93-95.DOI:10.3969/j.issn.1673-5412.2015.02.001.
34 Ambrosio S, Saccà CD, Amente S, et al.Lysine-specific demethylase LSD1 regulates autophagy in neuroblastoma through SESN2-dependent pathway[J].Oncogene, advance online publication, 7 August 2017, 1-11.DOI:10.1038/onc.2017.267.
35 Fan Chenghe, Liu Yuanyuan, Zhao Mingming, et al.Autophagy inhibits C2-ceramide-mediated cell death by decreasing the reactive oxygen species levels in SH-SY5Y cells[J].Neurosci Lett, 2017, 651(2):198-206.DOI:10.1016/j.neulet.2017.03.006.
36 Hagenbuchner Judith, Lungkofler Lorena, Kiechl-Kohlendorfer Ursula, et al.The tubulin inhibitor MG-2477 induces autophagy-regulated cell death, ROS accumulation and activation of FOXO3 in neuroblastoma[J].Oncotarget, 2017, 8(19):32009-32026.DOI:10.18632/oncotarget.16434.
37 Bastola Tonking, An Ren-Bo, Kim Youn-Chul, et al.Cearoin induces autophagy, ERK activation and apoptosis via ROS generation in SH-SY5Y neuroblastoma cells.Molecules, advance online publication, 2017, 22(2):242-249.DOI:10.3390/molecules22020242.

相似文献/References:

[1]郭春宝,王珊,金先庆,等.Cochrane系统评价方法对神经母细胞瘤分子与生物标记物的Meta分析[J].临床小儿外科杂志,2008,7(01):2.
[2]未德成,王忠荣,张燕敏,等.脂氧合酶抑制剂NDGA对人神经母细胞瘤SK-N-SH细胞生物学特性的影响[J].临床小儿外科杂志,2008,7(01):3.
[3]陈新让,王家祥,余捷凯,等.基于支持向量机神经母细胞瘤血清蛋白质标记物的检测及临床应用[J].临床小儿外科杂志,2008,7(02):12.
[4]罗远建,金科,甘青,等.儿童神经母细胞瘤的影像学表现[J].临床小儿外科杂志,2007,6(02):22.
[5]李昆昆 金先庆 牟廷刚 陈建飞 赵利华 丁雄辉 孙艳辉 王士奇. ATRA耐药基因HA117相关蛋白在四种恶性肿瘤的表达及临床意义[J].临床小儿外科杂志,2011,10(04):250.
 [J].Journal of Clinical Pediatric Surgery,2011,10(03):250.
[6]沙永亮 吴晔明. 化疗及非化疗组神经母细胞瘤干细胞标志物的表达及意义[J].临床小儿外科杂志,2011,10(04):254.
 [J].Journal of Clinical Pediatric Surgery,2011,10(03):254.
[7]刘涛 韩英 祝秀丹 王焕民 秦红 邹焱. Wnt—5a基因在神经母细胞瘤中的表达及意义[J].临床小儿外科杂志,2011,10(05):333.
 [J].Journal of Clinical Pediatric Surgery,2011,10(03):333.
[8]顾 涛 鹿洪亭 董 蒨.Kai1/CD82表达水平与神经母细胞瘤转移的关系探讨[J].临床小儿外科杂志,2013,12(02):100.[doi:10.3969/j.issn.1671— 6353.2013.02.007]
 GU Tao,LU Hong-ting,DONG Qian.The relationship between Kai1/CD82 expression and metastasis of neuroblastoma[J].Journal of Clinical Pediatric Surgery,2013,12(03):100.[doi:10.3969/j.issn.1671— 6353.2013.02.007]
[9]邢莉莉,吴晔明,张弛.熊果酸对神经母细胞瘤细胞增殖凋亡及 MYCN表达的影响[J].临床小儿外科杂志,2013,12(03):196.[doi:10.3969/j.issn.1671—6353.2013.03.010]
 XING Li li,WU Ye ming,ZHANG Chi..Ursolic acid effects proliferation、apoptosis and MYCN expression of neuroblastoma cell[J].Journal of Clinical Pediatric Surgery,2013,12(03):196.[doi:10.3969/j.issn.1671—6353.2013.03.010]
[10]张雁冰 刘朝阳 卢其 周小渔. RNA干扰对神经母细胞瘤细胞VEGFA的mRNA表达的影响[J].临床小儿外科杂志,2013,12(06):471.

备注/Memo

收稿日期:2018-01-15。
基金项目:哈尔滨市科技局科技创新人才研究专项基金后备人才项目资助(编号:2014RFQGJ124)
通讯作者:曲志博,Email:zhiboqu@126.com

更新日期/Last Update: 1900-01-01