Ou Wenhui,Xiao Wenfeng,Xie Xinquan,et al.Relationship between INSL3-RXFP2 and reproductive system[J].Journal of Clinical Pediatric Surgery,,22():192-196.[doi:10.3760/cma.j.cn101785-202010031-018]
Relationship between INSL3-RXFP2 and reproductive system
- Keywords:
- Insulin-like Factor 3; Relaxin Family Peptide Receptor 2; Cryptorchidism; Male Reproductive System; Female Reproductive System
- Abstract:
- Insulin-like factor 3(INSL3)is predominantly secreted by Leydig’s cell in males and theca cells in females.Its specific receptor,relaxin family peptide receptor 2(RXFP2),is expressed in gubernacular,germ and Leydig’s cells.RXFP2 is also expressed in ovary and theca cells.Abnormity of INSL3-RXFP2 complex is related to reproductive disease in both males and females.This review summarized the latest researches about the relationship between INSL3-RXFP2 complex and reproductive system.
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Memo
收稿日期:2020-10-21。
基金项目:国家自然科学基金青年项目(81801432);广东省自然科学基金(2022A1515010407、2020A1515010135、2018A030307045);广东省科技专项资金("大专项+任务清单")(STKJ2021119); 汕头市医疗卫生科技计划项目(汕府科【2020】58-35)
通讯作者:李建宏,Email:jianhongli2013@163.com